ul_1639----
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PPBD protein
Gene name DAB1( Description: dishevelled associated activator of morphogenesis 2. )
Synonyms KIAA0381; MGC90515; RP1-278E11.1; dJ90A20A.1
GO annotations GO_component:
GO_function:
GO_process: cell differentiation; nervous system development
RefSeq accession NP_066566
SwissProt accession O75553
Substrate protein
Gene name APLP1( Description: amyloid beta (A4) precursor-like protein 1. )
Synonyms APLP; APLP-1
GO annotations GO_component: basement membrane [PMID 9521588]; coated pit; integral to membrane; plasma membrane
GO_function:copper ion binding; heparin binding; metal ion binding; protein binding [PMID 14563850] [PMID 16169070]; zinc ion binding
GO_process: apoptosis; cell adhesion; cell death; endocytosis; nervous system development [PMID 9521588]; organ morphogenesis [PMID 9521588]
RefSeq accession NP_005157
SwissProt accession P51693
Sequence:(RefSeq accession:NP_005157; substrate region highlighted if known)
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MGPASPAARG LSRRPGQPPL PLLLPLLLLL LRAQPAIGSL AGGSPGAAEA PGSAQVAGLC
GRLTLHRDLR TGRWEPDPQR SRRCLRDPQR VLEYCRQMYP ELQIARVEQA TQAIPMERWC
GGSRSGSCAH PHHQVVPFRC LPGEFVSEAL LVPEGCRFLH QERMDQCESS TRRHQEAQEA
CSSQGLILHG SGMLLPCGSD RFRGVEYVCC PPPGTPDPSG TAVGDPSTRS WPPGSRVEGA
EDEEEEESFP QPVDDYFVEP PQAEEEEETV PPPSSHTLAV VGKVTPTPRP TDGVDIYFGM
PGEISEHEGF LRAKMDLEER RMRQINEVMR EWAMADNQSK NLPKADRQAL NEHFQSILQT
LEEQVSGERQ RLVETHATRV IALINDQRRA ALEGFLAALQ ADPPQAERVL LALRRYLRAE
QKEQRHTLRH YQHVAAVDPE KAQQMRFQVH THLQVIEERV NQSLGLLDQN PHLAQELRPQ
IQELLHSEHL GPSELEAPAP GGSSEDKGGL QPPDSKDDTP MTLPKGSTEQ DAASPEKEKM
NPLEQYERKV NASVPRGFPF HSSEIQRDEL APAGTGVSRE AVSGLLIMGA GGGSLIVLSM
LLLRRKKPYG AISHGVVEVD PMLTLEEQQL RELQRHGYEN PTYRFLEERP
Records:
Category Evidence Reference
A Peptide library Morris SM, Cooper JA., Signal transducer and activator of transcription (STAT)-induced STAT inhibitor 1 (SSI-1)/suppressor of cytokine signaling 1 (SOCS1) inhibits insulin signal transduction pathway through modulating insulin receptor substrate 1 (IRS-1) phosphorylation., [11247302]
End of Record Details