ul_1640----
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PPBD protein
Gene name DAB1( Description: dishevelled associated activator of morphogenesis 2. )
Synonyms KIAA0381; MGC90515; RP1-278E11.1; dJ90A20A.1
GO annotations GO_component:
GO_function:
GO_process: cell differentiation; nervous system development
RefSeq accession NP_066566
SwissProt accession O75553
Substrate protein
Gene name APLP2( Description: amyloid beta (A4) precursor-like protein 2. )
Synonyms APPH; APPL2; Amyloid protein homolog; CDEBP; CDEI box-binding protein
GO annotations GO_component: integral to membrane [PMID 8485127]; membrane; nucleus [PMID 7702756]
GO_function:binding; DNA binding [PMID 7702756]; protein binding [PMID 8855266]; serine-type endopeptidase inhibitor activity
GO_process: G-protein coupled receptor protein signaling pathway [PMID 8220435]
RefSeq accession NP_001633
SwissProt accession Q06481
Sequence:(RefSeq accession:NP_001633; substrate region highlighted if known)
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MAATGTAAAA ATGRLLLLLL VGLTAPALAL AGYIEALAAN AGTGFAVAEP QIAMFCGKLN
MHVNIQTGKW EPDPTGTKSC FETKEEVLQY CQEMYPELQI TNVMEANQRV SIDNWCRRDK
KQCKSRFVTP FKCLVGEFVS DVLLVPEKCQ FFHKERMEVC ENHQHWHTVV KEACLTQGMT
LYSYGMLLPC GVDQFHGTEY VCCPQTKIIG SVSKEEEEED EEEEEEEDEE EDYDVYKSEF
PTEADLEDFT EAAVDEDDED EEEGEEVVED RDYYYDTFKG DDYNEENPTE PGSDGTMSDK
EITHDVKAVC SQEAMTGPCR AVMPRWYFDL SKGKCVRFIY GGCGGNRNNF ESEDYCMAVC
KAMIPPTPLP TNDVDVYFET SADDNEHARF QKAKEQLEIR HRNRMDRVKK EWEEAELQAK
NLPKAERQTL IQHFQAMVKA LEKEAASEKQ QLVETHLARV EAMLNDRRRM ALENYLAALQ
SDPPRPHRIL QALRRYVRAE NKDRLHTIRH YQHVLAVDPE KAAQMKSQVM THLHVIEERR
NQSLSLLYKV PYVAQEIQEE IDELLQEQRA DMDQFTASIS ETPVDVRVSS EESEEIPPFH
PFHPFPALPE NEDTQPELYH PMKKGSGVGE QDGGLIGAEE KVINSKNKVD ENMVIDETLD
VKEMIFNAER VGGLEEERES VGPLREDFSL SSSALIGLLV IAVAIATVIV ISLVMLRKRQ
YGTISHGIVE VDPMLTPEER HLNKMQNHGY ENPTYKYLEQ MQI
Records:
Category Evidence Reference
A Peptide library Morris SM, Cooper JA., Signal transducer and activator of transcription (STAT)-induced STAT inhibitor 1 (SSI-1)/suppressor of cytokine signaling 1 (SOCS1) inhibits insulin signal transduction pathway through modulating insulin receptor substrate 1 (IRS-1) phosphorylation., [11247302]
End of Record Details