ul_165----
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PPBD protein
Gene name YWHAB( Description: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide. )
Synonyms GW128; HS1; KCIP-1; Protein 1054; Protein kinase C inhibitor protein 1
GO annotations GO_component: cytoplasm [PMID 12963375]; perinuclear region [PMID 12963375]
GO_function:monooxygenase activity; protein domain specific binding
GO_process:
RefSeq accession NP_003395
SwissProt accession P31946
Substrate protein
Gene name RGS3
Synonyms RGP3; RGS3
GO annotations GO_component: cytosol [PMID 9858594]; membrane; nucleus
GO_function:GTPase activator activity [PMID 9858594]; protein binding; signal transducer activity
GO_process: inactivation of MAPK activity [PMID 8602223]; negative regulation of signal transduction; regulation of G-protein coupled receptor protein signaling pathway [PMID 9858594]
RefSeq accession NP_652759
SwissProt accession P49796
Sequence:(RefSeq accession:NP_652759; substrate region highlighted if known)
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1021
1081
MEWLSPDIAL PRRDEWTQTS PARKRITHAK VQGAGQLRLS IDAQDRVLLL HIIEGKGLIS
KQPGTCDPYV KISLIPEDSR LRHQKTQTVP DCRDPAFHEH FFFPVQEEDD QKRLLVTVWN
RASQSRQSGL IGCMSFGVKS LLTPDKEISG WYYLLGEHLG RTKHLKVARR RLRPLRDPLL
RMPGGGDTEN GKKLKITIPR GKDGFGFTIC CDSPVRVQAV DSGGPAERAG LQQLDTVLQL
NERPVEHWKC VELAHEIRSC PSEIILLVWR MVPQVKPGPD GGVLRRASCK STHDLQSPPN
KREKNCTHGV QARPEQRHSC HLVCDSSDGL LLGGWERYTE VAKRGGQHTL PALSRATAPT
DPNYIILAPL NPGSQLLRPV YQEDTIPEES GSPSKGKSYT GLGKKSRLMK TVQTMKGHGN
YQNCPVVRPH ATHSSYGTYV TLAPKVLVFP VFVQPLDLCN PARTLLLSEE LLLYEGRNKA
AEVTLFAYSD LLLFTKEDEP GRCDVLRNPL YLQSVKLQEG SSEDLKFCVL YLAEKAECLF
TLEAHSQEQK KRVCWCLSEN IAKQQQLAAS PPDSKMFETE ADEKREMALE EGKGPGAEDS
PPSKEPSPGQ ELPPGQDLPP NKDSPSGQEP APSQEPLSSK DSATSEGSPP GPDAPPSKDV
PPCQEPPPAQ DLSPCQDLPA GQEPLPHQDP LLTKDLPAIQ ESPTRDLPPC QDLPPSQVSL
PAKALTEDTM SSGDLLAATG DPPAAPRPAF VIPEVRLDST YSQKAGAEQG CSGDEEDAEE
AEEVEEGEEG EEDEDEDTSD DNYGERSEAK RSSMIETGQG AEGGLSLRVQ NSLRRRTHSE
GSLLQEPRGP CFASDTTLHC SDGEGAASTW GMPSPSTLKK ELGRNGGSMH HLSLFFTGHR
KMSGADTVGD DDEASRKRKS KNLAKDMKNK LGIFRRRNES PGAPPAGKAD KMMKSFKPTS
EEALKWGESL EKLLVHKYGL AVFQAFLRTE FSEENLEFWL ACEDFKKVKS QSKMASKAKK
IFAEYIAIQA CKEVNLDSYT REHTKDNLQS VTRGCFDLAQ KRIFGLMEKD SYPRFLRSDL
YLDLINQKKM SPPL
Records:
Category Evidence Reference
A Inference Benzing T, Köttgen M, Johnson M, Schermer B, Zentgraf H, Walz G, Kim E., Interaction of 14-3-3 protein with regulator of G protein signaling 7 is dynamically regulated by tumor necrosis factor-alpha., [12077120]
End of Record Details