ul_1688----
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PPBD protein
Gene name ITGB1BP1
Synonyms ICAP-1; Integrin cytoplasmic domain-associated protein 1
GO annotations GO_component: membrane [PMID 9281591]
GO_function:protein C-terminus binding [PMID 9281591]
GO_process: cell adhesion [PMID 9281591]; cell-matrix adhesion [PMID 9281591]; protein kinase cascade [PMID 9813144]
RefSeq accession NP_004754
SwissProt accession O14713
Substrate protein
Gene name ITGB1
Synonyms CD29 antigen; Fibronectin receptor subunit beta; Integrin VLA-4 subunit beta
GO annotations GO_component: endoplasmic reticulum [PMID 11256614]; integral to membrane; integrin complex [PMID 9552005]; membrane; ruffle [PMID 11919189]
GO_function:identical protein binding [PMID 14681217]; protein binding; protein heterodimerization activity [PMID 9552005]; receptor activity
GO_process: cell adhesion; cell migration [PMID 11919189]; cell-matrix adhesion; cellular defense response [PMID 10201960]; development; homophilic cell adhesion [PMID 10201960]; integrin-mediated signaling pathway
RefSeq accession NP_391987
SwissProt accession P05556
GO Pathway:
GO:0007155     cell adhesion
Sequence:(RefSeq accession:NP_391987; substrate region highlighted if known)
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MNLQPIFWIG LISSVCCVFA QTDENRCLKA NAKSCGECIQ AGPNCGWCTN STFLQEGMPT
SARCDDLEAL KKKGCPPDDI ENPRGSKDIK KNKNVTNRSK GTAEKLKPED ITQIQPQQLV
LRLRSGEPQT FTLKFKRAED YPIDLYYLMD LSYSMKDDLE NVKSLGTDLM NEMRRITSDF
RIGFGSFVEK TVMPYISTTP AKLRNPCTSE QNCTSPFSYK NVLSLTNKGE VFNELVGKQR
ISGNLDSPEG GFDAIMQVAV CGSLIGWRNV TRLLVFSTDA GFHFAGDGKL GGIVLPNDGQ
CHLENNMYTM SHYYDYPSIA HLVQKLSENN IQTIFAVTEE FQPVYKELKN LIPKSAVGTL
SANSSNVIQL IIDAYNSLSS EVILENGKLS EGVTISYKSY CKNGVNGTGE NGRKCSNISI
GDEVQFEISI TSNKCPKKDS DSFKIRPLGF TEEVEVILQY ICECECQSEG IPESPKCHEG
NGTFECGACR CNEGRVGRHC ECSTDEVNSE DMDAYCRKEN SSEICSNNGE CVCGQCVCRK
RDNTNEIYSG KFCECDNFNC DRSNGLICGG NGVCKCRVCE CNPNYTGSAC DCSLDTSTCE
ASNGQICNGR GICECGVCKC TDPKFQGQTC EMCQTCLGVC AEHKECVQCR AFNKGEKKDT
CTQECSYFNI TKVESRDKLP QPVQPDPVSH CKEKDVDDCW FYFTYSVNGN NEVMVHVVEN
PECPTGPDII PIVAGVVAGI VLIGLALLLI WKLLMIIHDR REFAKFEKEK MNAKWDTSLS
VAQPGVQWCD ISSLQPLTSR FQQFSCLSLP STWDYRVKIL FIRVP
Records:
Category Evidence Reference
A Inference Zhang J, Clatterbuck RE, Rigamonti D, Chang DD, Dietz HC., Interaction between krit1 and icap1alpha infers perturbation of integrin beta1-mediated angiogenesis in the pathogenesis of cerebral cavernous malformation., [11741838]
End of Record Details