ul_1706----
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PPBD protein
Gene name NUMB
Synonyms Protein S171; h-Numb
GO annotations GO_component: integral to plasma membrane [PMID 7596406]; membrane
GO_function:protein binding [PMID 16002321]
GO_process: development
RefSeq accession NP_001005743
SwissProt accession P49757
Substrate protein
Gene name LNX1( Description: ligand of numb-protein X 1. )
Synonyms EC 6.3.2.-; LNX; Ligand of Numb-protein X 1; MPDZ; Numb-binding protein 1; PDZRN2
GO annotations GO_component:
GO_function:ligase activity; metal ion binding; protein binding [PMID 16002321] [PMID 16189514]; zinc ion binding
GO_process: ubiquitin cycle
RefSeq accession NP_116011
SwissProt accession Q8TBB1
Sequence:(RefSeq accession:NP_116011; substrate region highlighted if known)
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MKALLLLVLP WLSPANYIDN VGNLHFLYSE LCKGAFHYGL TKDRKRRSQD GCPDGCASLT
ATAPSPEVSA AATISLMTDE PGLDNPAYVS SAEDGQPAIS PVDSGRSNRT RARPFERSTI
RSRSFKKINR ALSVLRRTKS GSAVANHADQ GRENSENTTA PEVFPRLYHL IPDGEITSIK
INRVDPSESL SIRLVGGSET PLVHIIIQHI YRDGVIARDG RLLPGDIILK VNGMDISNVP
HNYAVRLLRQ PCQVLWLTVM REQKFRSRNN GQAPDAYRPR DDSFHVILNK SSPEEQLGIK
LVRKVDEPGV FIFNVLDGGV AYRHGQLEEN DRVLAINGHD LRYGSPESAA HLIQASERRV
HLVVSRQVRQ RSPDIFQEAG WNSNGSWSPG PGERSNTPKP LHPTITCHEK VVNIQKDPGE
SLGMTVAGGA SHREWDLPIY VISVEPGGVI SRDGRIKTGD ILLNVDGVEL TEVSRSEAVA
LLKRTSSSIV LKALEVKEYE PQEDCSSPAA LDSNHNMAPP SDWSPSWVMW LELPRCLYNC
KDIVLRRNTA GSLGFCIVGG YEEYNGNKPF FIKSIVEGTP AYNDGRIRCG DILLAVNGRS
TSGMIHACLA RLLKELKGRI TLTIVSWPGT FL
Records:
Category Evidence Reference
A Inference Margolis B., The PTB Domain: The Name Doesn't Say It All., [10461172]
End of Record Details