ul_1861----
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PPBD protein
Gene name ABL1
Synonyms Abelson murine leukemia viral oncogene homolog 1; EC 2.7.10.2; c-ABL; p150
GO annotations GO_component: nucleus [PMID 8242749]
GO_function:ATP binding; DNA binding [PMID 8242749]; nucleotide binding; protein C-terminus binding [PMID 11971963]; protein-tyrosine kinase activity [PMID 10391249]; transferase activity
GO_process: DNA damage response, signal transduction resulting in induction of apoptosis [PMID 10391249]; intracellular signaling cascade; mismatch repair [PMID 10391249]; protein amino acid phosphorylation; regulation of progression through cell cycle [PMID 8242749]; regulation of transcription, DNA-dependent [PMID 8242749]; S-phase-specific transcription in mitotic cell cycle [PMID 8242749]
RefSeq accession NP_005148
SwissProt accession P00519
Substrate protein
Gene name Dok1( Description: docking protein 1. )
Synonyms AW557123; p62DOK
GO annotations GO_component: cellular_component
GO_function:insulin receptor binding; kinase activity; protein binding; transmembrane receptor protein tyrosine kinase signaling protein activity
GO_process: MAPKKK cascade; protein kinase cascade; Ras protein signal transduction; transmembrane receptor protein tyrosine kinase signaling pathway
RefSeq accession NP_034200
SwissProt accession
Sequence:(RefSeq accession:NP_034200; substrate region highlighted if known)
1
61
121
181
241
301
361
421
481
MNGAVMEGPL FLQSQRFGTK RWRKTWAVLY PASPHGVARL EFFDHKGSSS RGGRGGSRRL
DCKMIRLAEC VSVVPVTVES PPEPGAAAFR LDTAQRSHLL AADAVSSTAW VQTLCRTAFP
KGGWALAQTE NQPKFSALEM LENSLYSPTW EGSQFWVTSQ KTEASERCGL QGSYILRVEA
EKLTLLTLGA QSQILEPLLF WPYTLLRRYG RDKVMFSFEA GRRCPSGPGT FTFQTSQGND
IFQAVEAAIQ QQKAQGKVGQ AQDILRTDSH DGETEGKTVP PPVPQDPLGS PPALYAEPLD
SLRIPPGPSQ DSVYSDPLGS TPAGAGEGVH SKKPLYWDLY GHVQQQLLKT KLTDSKEDPI
YDEPEGLAPA PPRGLYDLPQ EPRDAWWCQA RLKEEGYELP YNPATDDYAV PPPRSPKPAP
APKPQGLILP ESGTTRGSGS KGFSSDTALY SQVQKSGTSG AWDCGLSKVG NDRAGVKSEG
ST
Records:
Category Evidence Reference
A Inference Yamanashi Y, Baltimore D., Identification of the Abl- and rasGAP-associated 62 kDa protein as a docking protein, Dok, [9008161]
End of Record Details