ul_1867----
Record details: Hide
PPBD protein
Gene name ABL1
Synonyms Abelson murine leukemia viral oncogene homolog 1; EC 2.7.10.2; c-ABL; p150
GO annotations GO_component: nucleus [PMID 8242749]
GO_function:ATP binding; DNA binding [PMID 8242749]; nucleotide binding; protein C-terminus binding [PMID 11971963]; protein-tyrosine kinase activity [PMID 10391249]; transferase activity
GO_process: DNA damage response, signal transduction resulting in induction of apoptosis [PMID 10391249]; intracellular signaling cascade; mismatch repair [PMID 10391249]; protein amino acid phosphorylation; regulation of progression through cell cycle [PMID 8242749]; regulation of transcription, DNA-dependent [PMID 8242749]; S-phase-specific transcription in mitotic cell cycle [PMID 8242749]
RefSeq accession NP_005148
SwissProt accession P00519
Substrate protein
Gene name Dab1( Description: disabled homolog 1 (Drosophila). )
Synonyms AI956902; C630028C02Rik; scm; scr; scrambler; yot
GO annotations GO_component: intracellular
GO_function:phospholipid binding; protein binding; SH2 domain binding
GO_process: cell differentiation; central nervous system development; development; negative regulation of cell adhesion; nervous system development; neuron migration; positive regulation of protein kinase activity; protein kinase cascade; small GTPase mediated signal transduction
RefSeq accession NP_796233
SwissProt accession
GO Pathway:
GO:0007417     central nervous system development
Sequence:(RefSeq accession:NP_796233; substrate region highlighted if known)
1
61
121
181
241
301
361
421
481
541
MSTETELQVA VKTSAKKDSR KKGQDRSEAT LIKRFKGEGV RYKAKLIGID EVSAARGDKL
CQDSMMKLKG VVAGARSKGE HKQKIFLTIS FGGIKIFDEK TGALQHHHAV HEISYIAKDI
TDHRAFGYVC GKEGNHRFVA IKTAQAAEPV ILDLRDLFQL IYELKQREEL EKKAQKDKQC
EQAVYQTILE EDVEDPVYQY IVFEAGHEPI RDPETEENIY QVPTSQKKEG VYDVPKSQPV
SAVTQLELFG DMSTPPDITS PPTPATPGDA FLPSSSQTLP GSADVFGSMS FGTAAVPSGY
VAMGAVLPSF WGQQPLVQQQ IAMGAQPPVA QVIPGAQPIA WGQPGLFPAT QQAWPTVAGQ
FPPAAFMPTQ TVMPLAAAMF QGPLTPLATV PGTNDSARSS PQSDKPRQKM GKESFKDFQM
VQPPPVPSRK PDQPSLTCTS EAFSSYFNKV GVAQDTDDCD DFDISQLNLT PVTSTTPSTN
SPPTPAPRQS SPSKSSASHV SDPTADDIFE EGFESPSKSE EQEAPDGSQA SSTSDPFGEP
SGEPSGDNIS PQDGS
Records:
Category Evidence Reference
A Inference Howell BW, Gertler FB, Cooper JA., Mouse disabled (mDab1): a Src binding protein implicated in neuronal development, [9009273]
End of Record Details