ul_1889----
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PPBD protein
Gene name ABL1
Synonyms Abelson murine leukemia viral oncogene homolog 1; EC 2.7.10.2; c-ABL; p150
GO annotations GO_component: nucleus [PMID 8242749]
GO_function:ATP binding; DNA binding [PMID 8242749]; nucleotide binding; protein C-terminus binding [PMID 11971963]; protein-tyrosine kinase activity [PMID 10391249]; transferase activity
GO_process: DNA damage response, signal transduction resulting in induction of apoptosis [PMID 10391249]; intracellular signaling cascade; mismatch repair [PMID 10391249]; protein amino acid phosphorylation; regulation of progression through cell cycle [PMID 8242749]; regulation of transcription, DNA-dependent [PMID 8242749]; S-phase-specific transcription in mitotic cell cycle [PMID 8242749]
RefSeq accession NP_005148
SwissProt accession P00519
Substrate protein
Gene name NEDD9
Synonyms CAS-L; CRK-associated substrate-related protein; CasL; HEF1; Protein NEDD9; Renal carcinoma antigen NY-REN-12; p105
GO annotations GO_component: cytoplasm [PMID 9584194]; cytoskeleton; nucleus [PMID 8668148]; spindle [PMID 9584194]
GO_function:protein binding [PMID 11827972]
GO_process: actin filament bundle formation [PMID 11827972]; cell adhesion [PMID 9584194]; cell cycle; cell division; cytoskeleton organization and biogenesis [PMID 11827972]; integrin-mediated signaling pathway [PMID 11827972]; mitosis; regulation of cell growth; regulation of progression through cell cycle [PMID 9584194]; signal transduction [PMID 8668148]
RefSeq accession NP_006394
SwissProt accession Q14511
GO Pathway:
GO:0007229     integrin-mediated signaling pathway
Sequence:(RefSeq accession:NP_006394; substrate region highlighted if known)
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MKYKNLMARA LYDNVPECAE ELAFRKGDIL TVIEQNTGGL EGWWLCSLHG RQGIVPGNRV
KLLIGPMQET ASSHEQPASG LMQQTFGQQK LYQVPNPQAA PRDTIYQVPP SYQNQGIYQV
PTGHGTQEQE VYQVPPSVQR SIGGTSGPHV GKKVITPVRT GHGYVYEYPS RYQKDVYDIP
PSHTTQGVYD IPPSSAKGPV FSVPVGEIKP QGVYDIPPTK GVYAIPPSAC RDEAGLREKD
YDFPPPMRQA GRPDLRPEGV YDIPPTCTKP AGKDLHVKYN CDIPGAAEPV ARRHQSLSPN
HPPPQLGQSV GSQNDAYDVP RGVQFLEPPA ETSEKANPQE RDGVYDVPLH NPPDAKGSRD
LVDGINRLSF SSTGSTRSNM STSSTSSKES SLSASPAQDK RLFLDPDTAI ERLQRLQQAL
EMGVSSLMAL VTTDWRCYGY MERHINEIRT AVDKVELFLK EYLHFVKGAV ANAACLPELI
LHNKMKRELQ RVEDSHQILS QTSHDLNECS WSLNILAINK PQNKCDDLDR FVMVAKTVPD
DAKQLTTTIN TNAEALFRPG PGSLHLKNGP ESIMNSTEYP HGGSQGQLLH PGDHKAQAHN
KALPPGLSKE QAPDCSSSDG SERSWMDDYD YVHLQGKEEF ERQQKELLEK ENIMKQNKMQ
LEHHQLSQFQ LLEQEITKPV ENDISKWKPS QSLPTTNSGV SAQDRQLLCF YYDQCETHFI
SLLNAIDALF SCVSSAQPPR IFVAHSKFVI LSAHKLVFIG DTLTRQVTAQ DIRNKVMNSS
NQLCEQLKTI VMATKMAALH YPSTTALQEM VHQVTDLSRN AQLFKRSLLE MATF
Records:
Category Evidence Reference
A Inference Iwata S, Ohashi Y, Kamiguchi K, Morimoto C., Beta 1-integrin-mediated cell signaling in T lymphocytes, [10808124]
End of Record Details