ul_1904----
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PPBD protein
Gene name ABL1
Synonyms Abelson murine leukemia viral oncogene homolog 1; EC 2.7.10.2; c-ABL; p150
GO annotations GO_component: nucleus [PMID 8242749]
GO_function:ATP binding; DNA binding [PMID 8242749]; nucleotide binding; protein C-terminus binding [PMID 11971963]; protein-tyrosine kinase activity [PMID 10391249]; transferase activity
GO_process: DNA damage response, signal transduction resulting in induction of apoptosis [PMID 10391249]; intracellular signaling cascade; mismatch repair [PMID 10391249]; protein amino acid phosphorylation; regulation of progression through cell cycle [PMID 8242749]; regulation of transcription, DNA-dependent [PMID 8242749]; S-phase-specific transcription in mitotic cell cycle [PMID 8242749]
RefSeq accession NP_005148
SwissProt accession P00519
Substrate protein
Gene name NFKBIA( Description: nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha. )
Synonyms
GO annotations GO_component:
GO_function:
GO_process:
RefSeq accession NP_001001472
SwissProt accession
Sequence:(RefSeq accession:NP_001001472; substrate region highlighted if known)
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MLSAQRPAEP PAVEGCEPPR KERQGGLLPP DDRHDSGLDS MKEEEYRQLV RELEDIRLQP
REPPARPHAW VQQLTEDGDT FLHLAIIHEE KALSLEVIRQ AAGDAAFLNF QNNLSQTPLH
LAVITDQAEI AEHLLKAGCD LDVRDFRGNT PLHIACQQGS LRSVSVLTQH CQPHHLLAVL
QATNYNGHTC LHLASIQGYL AVVEYLLSLG ADVNAQEPCN GRTALHLAVD LQNSDLVSLL
VKHGADVNKV TYQGYSPYQL TWGRDNASIQ EQLKLLTTAD LQILPESEDE ESSESEPEFT
EDELMYDDCC IGGRQLTF
Records:
Category Evidence Reference
A Mutagenesis Kawai H, Nie L, Yuan ZM., Inactivation of NF-kappaB-dependent cell survival, a novel mechanism for the proapoptotic function of c-Abl, [12167702]
End of Record Details