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PPBD protein
Gene name BLK( Description: biogenesis of lysosome-related organelles complex-1, subunit 3. )
Synonyms B lymphocyte kinase; BLOS3; EC 2.7.10.2; HPS8; p55-BLK
GO annotations GO_component:
GO_function:ATP binding; nucleotide binding; protein-tyrosine kinase activity [PMID 7845672]; transferase activity
GO_process: protein amino acid phosphorylation; protein kinase cascade [PMID 2404338]
RefSeq accession NP_001706
SwissProt accession P51451
Substrate protein
Gene name CD79A
Synonyms CD79a antigen; Ig-alpha; MB-1 membrane glycoprotein; Membrane-bound immunoglobulin-associated protein; Surface IgM-associated protein
GO annotations GO_component: integral to membrane; membrane
GO_function:transmembrane receptor activity
GO_process: cell surface receptor linked signal transduction [PMID 1538135]; defense response [PMID 1538135]
RefSeq accession NP_001774
SwissProt accession P11912
GO Pathway:
GO:0006468     protein amio acid phosphorylation
Sequence:(RefSeq accession:NP_001774; substrate region highlighted if known)
1
61
121
181
MPGGPGVLQA LPATIFLLFL LSAVYLGPGC QALWMHKVPA SLMVSLGEDA HFQCPHNSSN
NANVTWWRVL HGNYTWPPEF LGPGEDPNGT LIIQNVNKSH GGIYVCRVQE GNESYQQSCG
TYLRVRQPPP RPFLDMGEGT KNRIITAEGI ILLFCAVVPG TLLLFRKRWQ NEKLGLDAGD
EYEDENLYEG LNLDDCSMYE DISRGLQGTY QDVGSLNIGD VQLEKP
Records:
Category Evidence Reference
A Mutagenesis Saouaf SJ, Kut SA, Fargnoli J, Rowley RB, Bolen JB, Mahajan S., Reconstitution of the B cell antigen receptor signaling components in COS cells, [7592958]
End of Record Details