ul_1973----
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PPBD protein
Gene name BLK( Description: biogenesis of lysosome-related organelles complex-1, subunit 3. )
Synonyms B lymphocyte kinase; BLOS3; EC 2.7.10.2; HPS8; p55-BLK
GO annotations GO_component:
GO_function:ATP binding; nucleotide binding; protein-tyrosine kinase activity [PMID 7845672]; transferase activity
GO_process: protein amino acid phosphorylation; protein kinase cascade [PMID 2404338]
RefSeq accession NP_001706
SwissProt accession P51451
Substrate protein
Gene name FCGR2A( Description: Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide. )
Synonyms CD32 antigen; CDw32; Fc-gamma RII-a; Fc-gamma-RIIa; FcRII-a; IgG Fc receptor II-a
GO annotations GO_component: integral to membrane; plasma membrane [PMID 2139735]
GO_function:IgG binding; receptor activity; receptor signaling protein activity
GO_process: immune response
RefSeq accession NP_067674
SwissProt accession P12318
GO Pathway:
GO:0006955     immune response
Sequence:(RefSeq accession:NP_067674; substrate region highlighted if known)
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MTMETQMSQN VCPRNLWLLQ PLTVLLLLAS ADSQAAPPKA VLKLEPPWIN VLQEDSVTLT
CQGARSPESD SIQWFHNGNL IPTHTQPSYR FKANNNDSGE YTCQTGQTSL SDPVHLTVLS
EWLVLQTPHL EFQEGETIML RCHSWKDKPL VKVTFFQNGK SQKFSHLDPT FSIPQANHSH
SGDYHCTGNI GYTLFSSKPV TITVQVPSMG SSSPMGIIVA VVIATAVAAI VAAVVALIYC
RKKRISANST DPVKAAQFEP PGRQMIAIRK RQLEETNNDY ETADGGYMTL NPRAPTDDDK
NIYLTLPPND HVNSNN
Records:
Category Evidence Reference
A Inference Bewarder N, Weinrich V, Budde P, Hartmann D, Flaswinkel H, Reth M, Frey J., In vivo and in vitro specificity of protein tyrosine kinases for immunoglobulin G receptor (FcgammaRII) phosphorylation, [8756631]
End of Record Details