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PPBD protein
Gene name BLNK( Description: B-cell linker. )
Synonyms B-cell adapter containing a SH2 domain protein; B-cell adapter containing a Src homology 2 domain protein; BASH; BLNK-s; Cytoplasmic adapter protein; Ly57; MGC111051; SLP-65; SLP65; Src homology 2 domain-containing leukocyte protein of 65 kDa
GO annotations GO_component:
GO_function:
GO_process: B cell activation; intracellular signaling cascade
RefSeq accession NP_037446
SwissProt accession Q8WV28
Substrate protein
Gene name CD79A( Description: CD79A antigen (immunoglobulin-associated alpha). )
Synonyms Ig-alpha; Iga; Ly-54; Ly54; mb-1
GO annotations GO_component: B cell receptor complex; external side of plasma membrane; membrane; multivesicular body
GO_function:protein binding; transmembrane receptor activity
GO_process: B cell receptor signaling pathway; cell surface receptor linked signal transduction
RefSeq accession NP_031681
SwissProt accession
GO Pathway:
GO:0050853     B cell receptor signaling pathway
Sequence:(RefSeq accession:NP_031681; substrate region highlighted if known)
1
61
121
181
MPGGLEALRA LPLLLFLSYA CLGPGCQALR VEGGPPSLTV NLGEEARLTC ENNGRNPNIT
WWFSLQSNIT WPPVPLGPGQ GTTGQLFFPE VNKNHRGLYW CQVIENNILK RSCGTYLRVR
NPVPRPFLDM GEGTKNRIIT AEGIILLFCA VVPGTLLLFR KRWQNEKFGV DMPDDYEDEN
LYEGLNLDDC SMYEDISRGL QGTYQDVGNL HIGDAQLEKP
Records:
Category Evidence Reference
A Peptide library Engels N, Wollscheid B, Wienands J., Association of SLP-65/BLNK with the B cell antigen receptor through a non-ITAM tyrosine of Ig-alpha, [11449366]
End of Record Details