ul_2----

Record details:

PPBD protein

Gene name	LOC284100
Synonyms
GO annotations	GO_component: GO_function: GO_process:
RefSeq accession	XP_375443
SwissProt accession	A2RUB5

Substrate protein

Gene name	CBL( Description: Bcl-associated death promoter. )
Synonyms	AI325008; Bbc2; Casitas B-lineage lymphoma proto-oncogene; EC 6.3.2.-; Proto-oncogene c-CBL; RING finger protein 55; Signal transduction protein CBL
GO annotations	GO_component: mitochondrion GO_function:protein binding GO_process: apoptosis; glucose catabolism; glucose homeostasis; induction of apoptosis; induction of apoptosis by extracellular signals; positive regulation of B cell differentiation; positive regulation of T cell differentiation; regulation of apoptosis
RefSeq accession	NP_031548
SwissProt accession	P22681

Sequence:(RefSeq accession:NP_031548; substrate region highlighted if known)

1
61
121
181

MGTPKQPSLA PAHALGLRKS DPGIRSLGSD AGGRRWRPAA QSMFQIPEFE PSEQEDASAT
DRGLGPSLTE DQPGPYLAPG LLGSNIHQQG RAATNSHHGG AGAMETRSRH SSYPAGTEED
EGMEEELSPF RGRSRSAPPN LWAAQRYGRE LRRMSDEFEG SFKGLPRPKS AGTATQMRQS
AGWTRIIQSW WDRNLGKGGS TPSQ

Records:

Category	Evidence	Reference
A	Mutagenesis	Zhang Z, Elly C, Altman A, Liu YC., Dual regulation of T cell receptor-mediated signaling by oncogenic Cbl mutant 70Z., [9988730]

End of Record Details