ul_20----
Record details: Hide
PPBD protein
Gene name SFN( Description: stratifin. )
Synonyms Epithelial cell marker protein 1; Stratifin; YWHAS
GO annotations GO_component: cytoplasm [PMID 10767298]; extracellular space [PMID 8515476]
GO_function:protein domain specific binding; protein kinase C inhibitor activity [PMID 8515476]
GO_process: cell proliferation [PMID 10767298]; negative regulation of protein kinase activity [PMID 8515476]; regulation of progression through cell cycle [PMID 10767298]; signal transduction [PMID 8515476]
RefSeq accession NP_006133
SwissProt accession P31947
Substrate protein
Gene name CSF2RB( Description: colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage). )
Synonyms CD131; CD131 antigen; CDw131; GM-CSF/IL-3/IL-5 receptor common beta-chain; IL3RB; IL5RB
GO annotations GO_component: granulocyte macrophage colony-stimulating factor receptor complex [PMID 9410898]; membrane
GO_function:interleukin-3 receptor activity [PMID 9410898]; interleukin-5 receptor activity [PMID 9410898]; receptor activity [PMID 9410898]
GO_process: cytokine and chemokine mediated signaling pathway; respiratory gaseous exchange [PMID 9410898]; signal transduction [PMID 1702217]
RefSeq accession NP_000386
SwissProt accession P32927
Sequence:(RefSeq accession:NP_000386; substrate region highlighted if known)
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
MVLAQGLLSM ALLALCWERS LAGAEETIPL QTLRCYNDYT SHITCRWADT QDAQRLVNVT
LIRRVNEDLL EPVSCDLSDD MPWSACPHPR CVPRRCVIPC QSFVVTDVDY FSFQPDRPLG
TRLTVTLTQH VQPPEPRDLQ ISTDQDHFLL TWSVALGSPQ SHWLSPGDLE FEVVYKRLQD
SWEDAAILLS NTSQATLGPE HLMPSSTYVA RVRTRLAPGS RLSGRPSKWS PEVCWDSQPG
DEAQPQNLEC FFDGAAVLSC SWEVRKEVAS SVSFGLFYKP SPDAGEEECS PVLREGLGSL
HTRHHCQIPV PDPATHGQYI VSVQPRRAEK HIKSSVNIQM APPSLNVTKD GDSYSLRWET
MKMRYEHIDH TFEIQYRKDT ATWKDSKTET LQNAHSMALP ALEPSTRYWA RVRVRTSRTG
YNGIWSEWSE ARSWDTESVL PMWVLALIVI FLTIAVLLAL RFCGIYGYRL RRKWEEKIPN
PSKSHLFQNG SAELWPPGSM SAFTSGSPPH QGPWGSRFPE LEGVFPVGFG DSEVSPLTIE
DPKHVCDPPS GPDTTPAASD LPTEQPPSPQ PGPPAASHTP EKQASSFDFN GPYLGPPHSR
SLPDILGQPE PPQEGGSQKS PPPGSLEYLC LPAGGQVQLV PLAQAMGPGQ AVEVERRPSQ
GAAGSPSLES GGGPAPPALG PRVGGQDQKD SPVAIPMSSG DTEDPGVASG YVSSADLVFT
PNSGASSVSL VPSLGLPSDQ TPSLCPGLAS GPPGAPGPVK SGFEGYVELP PIEGRSPRSP
RNNPVPPEAK SPVLNPGERP ADVSPTSPQP EGLLVLQQVG DYCFLPGLGP GPLSLRSKPS
SPGPGPEIKN LDQAFQVKKP PGQAVPQVPV IQLFKALKQQ DYLSLPPWEV NKPGEVC
Records:
Category Evidence Reference
A Mutagenesis Guthridge MA, Stomski FC, Barry EF, Winnall W, Woodcock JM, McClure BJ, Dottore M, Berndt MC, Lopez AF., Site-specific serine phosphorylation of the IL-3 receptor is required for hemopoietic cell survival., [10949031]
End of Record Details