ul_2056----<table width="100%" border="0" cellpadding="5" cellspacing="1" bgcolor="#666666" >
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          <td width="91%" align="left"><strong>Record details:</strong> </td>
          <td width="9%" align="right"><a href="javascript:hide('ul_2056')" class="small">Hide</a></td>
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    <td colspan="2"><strong>PPBD protein </strong></td>
    
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        <td width="25%">Gene name </td>
        <td><a href="ppbd.php?s=CISH" title="PPBD proteins are named by using their Entrez Gene Name.">CISH</a>( Description: cytokine inducible SH2-containing protein. )</td>
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        <td>Synonyms </td>
        <td>CIS; CIS-1; G18; Protein G18; SOCS; Suppressor of cytokine signaling</td>
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        <td>GO annotations </td>
        <td>GO_component: <br>GO_function:<br>GO_process: <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0007242>intracellular signaling cascade</a> [PMID
                     <a target="_blank" href=http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=pubmed&list_uids=10902923>10902923</a>]; <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0009968>negative regulation of signal transduction</a>;
                     <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0001558>regulation of cell growth</a> [PMID <a target="_blank" href=http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=pubmed&list_uids=9465889>9465889</a>]</td>
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        <td>RefSeq accession </td>
        <td><a href="http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_659508" target="_blank" >NP_659508</a></td>
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        <td>SwissProt accession </td>
        <td><a href="http://www.expasy.org/uniprot/Q9NSE2" target="_blank" >Q9NSE2</a></td>
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    <td  colspan="2"><strong>Substrate protein </strong></td>
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        <td width="25%">Gene name </td>
        <td><a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=full_report&list_uids=3953
" target="_blank"  title="Substrate proteins are named by using their Entrez Gene Name.">LEPR</a></td>
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        <td>Synonyms </td>
        <td>CD295 antigen; HuB219; LEP-R; OB receptor; OB-R</td>
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        <td>GO annotations </td>
        <td>GO_component: <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0005887>integral to plasma membrane</a>; <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0016020>membrane</a><br>GO_function:<a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0004896>hematopoietin/interferon-class (D200-domain)</a>
                     <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0004896>cytokine receptor activity</a><br>GO_process: <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0007166>cell surface receptor linked signal</a>
                     <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0007166>transduction</a> [PMID <a target="_blank" href=http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=pubmed&list_uids=9537324>9537324</a>]; <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0007275>development</a> [PMID <a target="_blank" href=http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=pubmed&list_uids=9537324>9537324</a>];
                     <a target="_blank" href=http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0006112>energy reserve metabolism</a> [PMID <a target="_blank" href=http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=pubmed&list_uids=9537324>9537324</a>]</td>
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        <td>RefSeq accession </td>
        <td><a href="http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_002294" target="_blank" >NP_002294</a></td>
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        <td>SwissProt accession </td>
        <td><a href="http://www.expasy.org/uniprot/P48357" target="_blank" >P48357</a></td>
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    <td colspan="2" bgcolor="#CCCCCC"><strong>Sequence:</strong>(RefSeq accession:<a href="http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_002294" target="_blank" >NP_002294</a>; substrate region highlighted 
if known)</td></tr><tr bgcolor="#FFFFFF"><td colspan="2"><table align="center"><tr><td class="sequence" align="right">1<br>61<br>121<br>181<br>241<br>301<br>361<br>421<br>481<br>541<br>601<br>661<br>721<br>781<br>841<br>901<br>961<br>1021<br>1081<br>1141<br></td><td><span class="sequence">MICQKFCVVL LHWEFIYVIT AFNLSYPITP WRFKLSCMPP NSTYDYFLLP AGLSKNTSNS <br>NGHYETAVEP KFNSSGTHFS NLSKTTFHCC FRSEQDRNCS LCADNIEGKT FVSTVNSLVF <br>QQIDANWNIQ CWLKGDLKLF ICYVESLFKN LFRNYNYKVH LLYVLPEVLE DSPLVPQKGS <br>FQMVHCNCSV HECCECLVPV PTAKLNDTLL MCLKITSGGV IFQSPLMSVQ PINMVKPDPP <br>LGLHMEITDD GNLKISWSSP PLVPFPLQYQ VKYSENSTTV IREADKIVSA TSLLVDSILP <br>GSSYEVQVRG KRLDGPGIWS DWSTPRVFTT QDVIYFPPKI LTSVGSNVSF HCIYKKENKI <br>VPSKEIVWWM NLAEKIPQSQ YDVVSDHVSK VTFFNLNETK PRGKFTYDAV YCCNEHECHH <br>RYAELYVIDV NINISCETDG YLTKMTCRWS TSTIQSLAES TLQLRYHRSS LYCSDIPSIH <br>PISEPKDCYL QSDGFYECIF QPIFLLSGYT MWIRINHSLG SLDSPPTCVL PDSVVKPLPP <br>SSVKAEITIN IGLLKISWEK PVFPENNLQF QIRYGLSGKE VQWKMYEVYD AKSKSVSLPV <br>PDLCAVYAVQ VRCKRLDGLG YWSNWSNPAY TVVMDIKVPM RGPEFWRIIN GDTMKKEKNV <br>TLLWKPLMKN DSLCSVQRYV INHHTSCNGT WSEDVGNHTK FTFLWTEQAH TVTVLAINSI <br>GASVANFNLT FSWPMSKVNI VQSLSAYPLN SSCVIVSWIL SPSDYKLMYF IIEWKNLNED <br>GEIKWLRISS SVKKYYIHDH FIPIEKYQFS LYPIFMEGVG KPKIINSFTQ DDIEKHQSDA <br>GLYVIVPVII SSSILLLGTL LISHQRMKKL FWEDVPNPKN CSWAQGLNFQ KPETFEHLFI <br>KHTASVTCGP LLLEPETISE DISVDTSWKN KDEMMPTTVV SLLSTTDLEK GSVCISDQFN <br>SVNFSEAEGT EVTYEDE<font color='red'>SQR QPFVKYATLI SNSK</font>PSETGE EQGLINSSVT KCFSSKNSPL <br>KDSFSNSSWE IEAQAFFILS DQHPNIISPH LTFSEGLDEL LKLEGNFPEE NNDKKSIYYL <br>GVTSIKKRES GVLLTDKSRV SCPFPAPCLF TDIRVLQDSC SHFVENNINL GTSSKKTFAS <br>YMPQFQTCST QTHKIMENKM CDLTV</span></td></tr></table></td></tr><tr>
    <td colspan="2" bgcolor="#CCCCCC"><strong>Records:</strong></td>
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                <td align="center"><b>Category</b></td>
                <td align="center"><b>Evidence</b></td>
                <td align="center"><b>Reference</b></td>
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                <td  align="center">A</td>
                <td  align="center">Peptide affinity isolation</td>
                <td  align="left"><a>Lavens D, Montoye T, Piessevaux J, Zabeau L, Vandekerckhove J, Gevaert K, Becker W, Eyckerman S, Tavernier J., A complex interaction pattern of CIS and SOCS2 with the leptin receptor, [<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16684815" target="_blank" >16684815</a>] </a></td>
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    <td colspan="2" bgcolor="#999999" align="right"><strong>End of Record Details</strong></td>
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