ul_21----
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PPBD protein
Gene name SFN( Description: stratifin. )
Synonyms Epithelial cell marker protein 1; Stratifin; YWHAS
GO annotations GO_component: cytoplasm [PMID 10767298]; extracellular space [PMID 8515476]
GO_function:protein domain specific binding; protein kinase C inhibitor activity [PMID 8515476]
GO_process: cell proliferation [PMID 10767298]; negative regulation of protein kinase activity [PMID 8515476]; regulation of progression through cell cycle [PMID 10767298]; signal transduction [PMID 8515476]
RefSeq accession NP_006133
SwissProt accession P31947
Substrate protein
Gene name HDAC4( Description: histone deacetylase 4. )
Synonyms HA6116; HD4; HDAC-A; HDACA; KIAA0288
GO annotations GO_component: cytoplasm [PMID 12711221]; histone deacetylase complex [PMID 12711221]; nucleus
GO_function:histone deacetylase activity [PMID 10523670]; hydrolase activity; transcription factor binding [PMID 12711221]; transcriptional repressor activity [PMID 10523670]
GO_process: B cell differentiation [PMID 12711221]; cell cycle; chromatin modification [PMID 12711221]; development; inflammatory response [PMID 12711221]; negative regulation of striated muscle development [PMID 12711221]; nervous system development [PMID 12711221]; regulation of transcription, DNA-dependent [PMID 10523670]; transcription
RefSeq accession NP_006028
SwissProt accession P56524
GO Pathway:
GO:0006605     protein targeting
Sequence:(RefSeq accession:NP_006028; substrate region highlighted if known)
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961
1021
1081
MSSQSHPDGL SGRDQPVELL NPARVNHMPS TVDVATALPL QVAPSAVPMD LRLDHQFSLP
VAEPALREQQ LQQELLALKQ KQQIQRQILI AEFQRQHEQL SRQHEAQLHE HIKQQQEMLA
MKHQQELLEH QRKLERHRQE QELEKQHREQ KLQQLKNKEK GKESAVASTE VKMKLQEFVL
NKKKALAHRN LNHCISSDPR YWYGKTQHSS LDQSSPPQSG VSTSYNHPVL GMYDAKDDFP
LRKTASEPNL KLRSRLKQKV AERRSSPLLR RKDGPVVTAL KKRPLDVTDS ACSSAPGSGP
SSPNNSSGSV SAENGIAPAV PSIPAETSLA HRLVAREGSA APLPLYTSPS LPNITLGLPA
TGPSAGTAGQ QDTERLTLPA LQQRLSLFPG THLTPYLSTS PLERDGGAAH SPLLQHMVLL
EQPPAQAPLV TGLGALPLHA QSLVGADRVS PSIHKLRQHR PLGRTQSAPL PQNAQALQHL
VIQQQHQQFL EKHKQQFQQQ QLQMNKIIPK PSEPARQPES HPEETEEELR EHQALLDEPY
LDRLPGQKEA HAQAGVQVKQ EPIESDEEEA EPPREVEPGQ RQPSEQELLF RQQALLLEQQ
RIHQLRNYQA SMEAAGIPVS FGGHRPLSRA QSSPASATFP VSVQEPPTKP RFTTGLVYDT
LMLKHQCTCG SSSSHPEHAG RIQSIWSRLQ ETGLRGKCEC IRGRKATLEE LQTVHSEAHT
LLYGTNPLNR QKLDSKKLLG SLASVFVRLP CGGVGVDSDT IWNEVHSAGA ARLAVGCVVE
LVFKVATGEL KNGFAVVRPP GHHAEESTPM GFCYFNSVAV AAKLLQQRLS VSKILIVDWD
VHHGNGTQQA FYSDPSVLYM SLHRYDDGNF FPGSGAPDEV GTGPGVGFNV NMAFTGGLDP
PMGDAEYLAA FRTVVMPIAS EFAPDVVLVS SGFDAVEGHP TPLGGYNLSA RCFGYLTKQL
MGLAGGRIVL ALEGGHDLTA ICDASEACVS ALLGNELDPL PEKVLQQRPN ANAVRSMEKV
MEIHSKYWRC LQRTTSTAGR SLIEAQTCEN EEAETVTAMA SLSVGVKPAE KRPDEEPMEE
EPPL
Records:
Category Evidence Reference
A Mutagenesis Wang AH, Kruhlak MJ, Wu J, Bertos NR, Vezmar M, Posner BI, Bazett-Jones DP, Yang XJ., Regulation of histone deacetylase 4 by binding of 14-3-3 proteins., [10958686]
End of Record Details