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PPBD protein
Gene name YWHAB( Description: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide. )
Synonyms GW128; HS1; KCIP-1; Protein 1054; Protein kinase C inhibitor protein 1
GO annotations GO_component: cytoplasm [PMID 12963375]; perinuclear region [PMID 12963375]
GO_function:monooxygenase activity; protein domain specific binding
GO_process:
RefSeq accession NP_003395
SwissProt accession P31946
Substrate protein
Gene name ZFP36( Description: zinc finger protein 36, C3H type, homolog (mouse). )
Synonyms G0/G1 switch regulatory protein 24; G0S24; GOS24; Growth factor-inducible nuclear protein NUP475; NUP475; Protein TIS11A; RNF162A; TIS11; TTP; Zfp-36; Zinc finger protein 36 homolog
GO annotations GO_component: cytoplasm [PMID 9703499]; cytosol [PMID 10751406]; nucleus
GO_function:DNA binding; metal ion binding; mRNA binding [PMID 11782475]; protein binding [PMID 15231747]; single-stranded RNA binding [PMID 9703499]; zinc ion binding
GO_process: mRNA catabolism [PMID 10751406] [PMID 11782475]
RefSeq accession NP_003398
SwissProt accession P26651
Sequence:(RefSeq accession:NP_003398; substrate region highlighted if known)
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MDLTAIYESL LSLSPDVPVP SDHGGTESSP GWGSSGPWSL SPSDSSPSGV TSRLPGRSTS
LVEGRSCGWV PPPPGFAPLA PRLGPELSPS PTSPTATSTT PSRYKTELCR TFSESGRCRY
GAKCQFAHGL GELRQANRHP KYKTELCHKF YLQGRCPYGS RCHFIHNPSE DLAAPGHPPV
LRQSISFSGL PSGRRTSPPP PGLAGPSLSS SSFSPSSSPP PPGDLPLSPS AFSAAPGTPL
ARRDPTPVCC PSCRRATPIS VWGPLGGLVR TPSVQSLGSD PDEYASSGSS LGGSDSPVFE
AGVFAPPQPV AAPRRLPIFN RISVSE
Records:
Category Evidence Reference
A Inference Gringhuis SI, García-Vallejo JJ, van Het Hof B, van Dijk W., Convergent actions of I kappa B kinase beta and protein kinase C delta modulate mRNA stability through phosphorylation of 14-3-3 beta complexed with tristetraprolin., [16024783]
End of Record Details