ul_2281----
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PPBD protein
Gene name CRK( Description: v-crk sarcoma virus CT10 oncogene homolog (avian)-like. )
Synonyms
GO annotations GO_component: cytoplasm [PMID 10748058]; nucleus [PMID 10748058]
GO_function:protein binding [PMID 9788432] [PMID 9819391] [PMID 11278465] [PMID 16713569]; SH2 domain binding [PMID 9472046]; SH3/SH2 adaptor activity
GO_process: actin cytoskeleton organization and biogenesis [PMID 10748058]; cell motility; intracellular signaling cascade; regulation of transcription from RNA polymerase II promoter [PMID 10748058]
RefSeq accession NP_058431
SwissProt accession Q96GA9
Substrate protein
Gene name DOK4( Description: docking protein 4. )
Synonyms FLJ10488
GO annotations GO_component:
GO_function:insulin receptor binding
GO_process:
RefSeq accession NP_060580
SwissProt accession Q8TEW6
Sequence:(RefSeq accession:NP_060580; substrate region highlighted if known)
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MATNFSDIVK QGYVKMKSRK LGIYRRCWLV FRKSSSKGPQ RLEKYPDEKS VCLRGCPKVT
EISNVKCVTR LPKETKRQAV AIIFTDDSAR TFTCDSELEA EEWYKTLSVE CLGSRLNDIS
LGEPDLLAPG VQCEQTDRFN VFLLPCPNLD VYGECKLQIT HENIYLWDIH NPRVKLVSWP
LCSLRRYGRD ATRFTFEAGR MCDAGEGLYT FQTQEGEQIY QRVHSATLAI AEQHKRVLLE
MEKNVRLLNK GTEHYSYPCT PTTMLPRSAY WHHITGSQNI AEASSYAGEG YGAAQASSET
DLLNRFILLK PKPSQGDSSE AKTPSQ
Records:
Category Evidence Reference
A Inference Cai D, Dhe-Paganon S, Melendez PA, Lee J, Shoelson SE., Two new substrates in insulin signaling, IRS5/DOK4 and IRS6/DOK5, [12730241]
End of Record Details