ul_2345----
Record details: Hide
PPBD protein
Gene name CRKL( Description: v-crk sarcoma virus CT10 oncogene homolog (avian)-like. )
Synonyms Adapter molecule crk; p38
GO annotations GO_component:
GO_function:protein binding [PMID 9788432]; protein-tyrosine kinase activity [PMID 8361759]; SH3/SH2 adaptor activity [PMID 8798523]
GO_process: cell motility; intracellular signaling cascade [PMID 8361759]; JNK cascade [PMID 8798523]; protein amino acid phosphorylation; Ras protein signal transduction [PMID 8798523]
RefSeq accession NP_005198
SwissProt accession P46108
Substrate protein
Gene name EFS
Synonyms
GO annotations GO_component: cytoplasm [PMID 9349509]
GO_function:protein binding
GO_process: cell adhesion; intracellular signaling cascade [PMID 9349509]
RefSeq accession NP_005855
SwissProt accession O43281
Sequence:(RefSeq accession:NP_005855; substrate region highlighted if known)
1
61
121
181
241
301
361
421
481
541
MAIATSTQLA RALYDNTAES PQELSFRRGD VLRVLQREGA GGLDGWCLCS LHGQQGIVPA
NRVKLLPAGP APKPSLSPAS PAQPGSPYPA PDHSNEDQEV YVVPPPARPC PTSGPPAGPC
PPSPDLIYKI PRASGTQLAA PRDALEVYDV PPTALRVPSS GPYDCPASFS HPLTRVAPQP
PGEDDAPYDV PLTPKPPAEL EPDLEWEGGR EPGPPIYAAP SNLKRASALL NLYEAPEELL
ADGEGGGTDE GIYDVPLLGP EAPPSPEPPG ALASHDQDTL AQLLARSPPP PHRPRLPSAE
SLSRRPLPAL PVPEAPSPSP VPSPAPGRKG SIQDRPLPPP PPRLPGYGGP KVEGDPEGRE
MEDDPAGHHN EYEGIPMAEE YDYVHLKGMD KAQGSRPPDQ ACTGDPELPE RGMPAPQEAL
SPGEPLVVST GDLQLLYFYA GQCQSHYSAL QAAVAALMSS TQANQPPRLF VPHSKRVVVA
AHRLVFVGDT LGRLAASAPL RAQVRAAGTA LGQALRATVL AVKGAALGYP SSPAIQEMVQ
CVTELAGQAL QFTTLLTSLA P
Records:
Category Evidence Reference
A Inference Minegishi M, Tachibana K, Sato T, Iwata S, Nojima Y, Morimoto C., Structure and function of Cas-L, a 105-kD Crk-associated substrate-related protein that is involved in beta 1 integrin-mediated signaling in lymphocytes, [8879209]
End of Record Details