ul_2424----
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PPBD protein
Gene name CRKL( Description: v-crk sarcoma virus CT10 oncogene homolog (avian)-like. )
Synonyms
GO annotations GO_component:
GO_function:protein binding [PMID 9788432]; protein-tyrosine kinase activity [PMID 8361759]; SH3/SH2 adaptor activity [PMID 8798523]
GO_process: cell motility; intracellular signaling cascade [PMID 8361759]; JNK cascade [PMID 8798523]; protein amino acid phosphorylation; Ras protein signal transduction [PMID 8798523]
RefSeq accession NP_005198
SwissProt accession P46109
Substrate protein
Gene name GAB2( Description: GRB2-associated binding protein 2. )
Synonyms GRB2-associated binder 2; KIAA0571; pp100
GO annotations GO_component:
GO_function:
GO_process:
RefSeq accession NP_036428
SwissProt accession Q9UQC2
GO Pathway:
GO:0007242     intracellular signaling cascade
Sequence:(RefSeq accession:NP_036428; substrate region highlighted if known)
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MSGDPDVLEY YKNDHSKKPL RIINLNFCEQ VDAGLTFNKK ELQDSFVFDI KTSERTFYLV
AETEEDMNKW VQSICQICGF NQAEESTDSL RNVSSAGHGP RSSPAELSSS SQHLLRERKS
SAPSHSSQPT LFTFEPPVSN HMQPTLSTSA PQEYLYLHQC ISRRAENARS ASFSQGTRAS
FLMRSDTAVQ KLAQGNGHCV NGISGQVHGF YSLPKPSRHN TEFRDSTYDL PRSLASHGHT
KGSLTGSETD NEDVYTFKTP SNTLCREFGD LLVDNMDVPA TPLSAYQIPR TFTLDKNHNA
MTVATPGDSA IAPPPRPPKP SQAETPRWGS PQQRPPISEN SRSVAATIPR RNTLPAMDNS
RLHRASSCET YEYPQRGGES AGRSAESMSD GVGSFLPGKM IVGRSDSTNS EDNYVPMNPG
SSTLLAMERA GDNSQSVYIP MSPGAHHFDS LGYPSTTLPV HRGPSRGSEI QPPPVNRNLK
PDRKAKPTPL DLRNNTVIDE LPFKSPITKS WSRANHTFNS SSSQYCRPIS TQSITSTDSG
DSEENYVPMQ NPVSASPVPS GTNSPAPKKS TGSVDYLALD FQPSSPSPHR KPSTSSVTSD
EKVDYVQVDK EKTQALQNTM QEWTDVRQSS EPSKGAKL
Records:
Category Evidence Reference
A Mutagenesis Crouin C, Arnaud M, Gesbert F, Camonis J, Bertoglio J., A yeast two-hybrid study of human p97/Gab2 interactions with its SH2 domain-containing binding partners, [11334882]
End of Record Details