ul_2464----
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PPBD protein
Gene name CRKL( Description: v-crk sarcoma virus CT10 oncogene homolog (avian)-like. )
Synonyms
GO annotations GO_component:
GO_function:protein binding [PMID 9788432]; protein-tyrosine kinase activity [PMID 8361759]; SH3/SH2 adaptor activity [PMID 8798523]
GO_process: cell motility; intracellular signaling cascade [PMID 8361759]; JNK cascade [PMID 8798523]; protein amino acid phosphorylation; Ras protein signal transduction [PMID 8798523]
RefSeq accession NP_005198
SwissProt accession P46109
Substrate protein
Gene name IGFBP4( Description: insulin-like growth factor binding protein 4. )
Synonyms BP-4; HT29-IGFBP; IBP-4; IBP4; IGF-binding protein 4; IGFBP-4
GO annotations GO_component: extracellular region
GO_function:insulin-like growth factor binding
GO_process: cell proliferation [PMID 1377672]; DNA metabolism [PMID 1377672]; regulation of cell growth; signal transduction [PMID 1377672]; skeletal development [PMID 1377672]
RefSeq accession NP_001543
SwissProt accession P22692
Sequence:(RefSeq accession:NP_001543; substrate region highlighted if known)
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MLPLCLVAAL LLAAGPGPSL GDEAIHCPPC SEEKLARCRP PVGCEELVRE PGCGCCATCA
LGLGMPCGVY TPRCGSGLRC YPPRGVEKPL HTLMHGQGVC MELAEIEAIQ ESLQPSDKDE
GDHPNNSFSP CSAHDRRCLQ KHFAKIRDRS TSGGKMKVNG APREDARPVP QGSCQSELHR
ALERLAASQS RTHEDLYIIP IPNCDRNGNF HPKQCHPALD GQRGKCWCVD RKTGVKLPGG
LEPKGELDCH QLADSFRE
Records:
Category Evidence Reference
A Peptide affinity isolation Yaoi T, Chamnongpol S, Jiang X, Li X., Src homology 2 domain-based high throughput assays for profiling downstream molecules in receptor tyrosine kinase pathways, [16477079]
End of Record Details