ul_2494----
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PPBD protein
Gene name CSK( Description: c-src tyrosine kinase. )
Synonyms C-SRC kinase; EC 2.7.10.2; MGC117393; Protein-tyrosine kinase CYL
GO annotations GO_component: cytoplasm [PMID 8890164]; plasma membrane [PMID 10790433]
GO_function:ATP binding; nucleotide binding; protein C-terminus binding [PMID 8890164]; protein-tyrosine kinase activity [PMID 1945408]; transferase activity
GO_process: intracellular signaling cascade; protein amino acid phosphorylation [PMID 1945408]; regulation of progression through cell cycle [PMID 1377109]
RefSeq accession NP_004374
SwissProt accession P41240
Substrate protein
Gene name Ptpn18( Description: protein tyrosine phosphatase, non-receptor type 18. )
Synonyms FLP1; HSCF; PTP-HSCF; PTP-K1; Ptpk1
GO annotations GO_component: cytoplasm; nucleus
GO_function:hydrolase activity; non-membrane spanning protein tyrosine phosphatase activity; protein binding; protein tyrosine phosphatase activity
GO_process:
RefSeq accession NP_035336
SwissProt accession
Sequence:(RefSeq accession:NP_035336; substrate region highlighted if known)
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MSRHTDLVRS FLEQLEARDY REGAILAREF SDIKARSVAW KSEGVCSTKA GSRLGNTNKN
RYKDVVAYDE TRVILSLLQE EGHGDYINAN FIRGIDGSQA YIATQGPLPH TLLDFWRLVW
EFGVKVILMA CQETENGRRK CERYWAREQE PLKAGPFCIT LTKETTLNAD ITLRTLQVTF
QKEFRSVHQL QYMSWPDHGV PSSSDHILTM VEEARCLQGL GPGPLCVHCS AGCGRTGVLC
AVDYVRQLLL TQTIPPNFSL FQVVLEMRKQ RPAAVQTEEQ YRFLYHTVAQ LFSRTLQDTS
PHYQNLKENC APICKEAFSL RTSSALPATS RPPGGVLRSI SVPAPPTLPM ADTYAVVQKR
GASAGTGPGP RAPTSTDTPI YSQVAPRAQR PVAHTEDAQG TTALRRVPAD QNSSGPDAYE
EVTDGAQTGG LGFNLRIGRP KGPRDPPAEW TRV
Records:
Category Evidence Reference
A Mutagenesis Wang B, Lemay S, Tsai S, Veillette A., SH2 domain-mediated interaction of inhibitory protein tyrosine kinase Csk with protein tyrosine phosphatase-HSCF, [11158295]
End of Record Details