ul_2499----
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PPBD protein
Gene name CSK( Description: c-src tyrosine kinase. )
Synonyms C-SRC kinase; EC 2.7.10.2; MGC117393; Protein-tyrosine kinase CYL
GO annotations GO_component: cytoplasm [PMID 8890164]; plasma membrane [PMID 10790433]
GO_function:ATP binding; nucleotide binding; protein C-terminus binding [PMID 8890164]; protein-tyrosine kinase activity [PMID 1945408]; transferase activity
GO_process: intracellular signaling cascade; protein amino acid phosphorylation [PMID 1945408]; regulation of progression through cell cycle [PMID 1377109]
RefSeq accession NP_004374
SwissProt accession P41240
Substrate protein
Gene name CAV1( Description: caveolin 1, caveolae protein, 22kDa. )
Synonyms CAV; MSTP085; VIP21
GO annotations GO_component: caveolar membrane [PMID 15219854]; endoplasmic reticulum [PMID 11294831]; Golgi membrane [PMID 11294831]; integral to membrane; integral to plasma membrane [PMID 1360410]; lipid raft [PMID 11294831]; plasma membrane [PMID 11256614]
GO_function:cholesterol binding [PMID 11294831]; protein binding [PMID 10212252]; structural molecule activity [PMID 11865038]
GO_process: cholesterol homeostasis [PMID 11294831]; cholesterol transport [PMID 11294831]
RefSeq accession NP_001744
SwissProt accession Q03135
Sequence:(RefSeq accession:NP_001744; substrate region highlighted if known)
1
61
121
MSGGKYVDSE GHLYTVPIRE QGNIYKPNNK AMADELSEKQ VYDAHTKEID LVNRDPKHLN
DDVVKIDFED VIAEPEGTHS FDGIWKASFT TFTVTKYWFY RLLSALFGIP MALIWGIYFA
ILSFLHIWAV VPCIKSFLIE IQCISRVYSI YVHTVCDPLF EAVGKIFSNV RINLQKEI
Records:
Category Evidence Reference
A Mutagenesis Cao H, Courchesne WE, Mastick CC., A phosphotyrosine-dependent protein interaction screen reveals a role for phosphorylation of caveolin-1 on tyrosine 14: recruitment of C-terminal Src kinase, [11805080]
End of Record Details