ul_2501----
Record details: Hide
PPBD protein
Gene name CSK( Description: c-src tyrosine kinase. )
Synonyms C-SRC kinase; EC 2.7.10.2; MGC117393; Protein-tyrosine kinase CYL
GO annotations GO_component: cytoplasm [PMID 8890164]; plasma membrane [PMID 10790433]
GO_function:ATP binding; nucleotide binding; protein C-terminus binding [PMID 8890164]; protein-tyrosine kinase activity [PMID 1945408]; transferase activity
GO_process: intracellular signaling cascade; protein amino acid phosphorylation [PMID 1945408]; regulation of progression through cell cycle [PMID 1377109]
RefSeq accession NP_004374
SwissProt accession P41240
Substrate protein
Gene name DOK3( Description: docking protein 3. )
Synonyms FLJ22570; FLJ39939
GO annotations GO_component:
GO_function:insulin receptor binding
GO_process:
RefSeq accession NP_079148
SwissProt accession Q7L591
GO Pathway:
GO:0007242     intracellular signaling cascade
Sequence:(RefSeq accession:NP_079148; substrate region highlighted if known)
1
61
121
181
241
301
361
421
481
MTRGARLRSD ARAQLNQLSL DGGTGSGQKG KCEEFPSSLS SVSPGLEAAA LLLAVTMDPL
ETPIKDGILY QQHVKFGKKC WRKVWALLYA GGPSGVARLE SWEVRDGGLG AAGDRSAGPG
RRGERRVIRL ADCVSVLPAD GESCPRDTGA FLLTTTERSH LLAAQHRQAW MGPICQLAFP
GTGEASSGST DAQSPKRGLV PMEENSIYSS WQEVGEFPVV VQRTEAATRC QLKGPALLVL
GPDAIQLREA KGTQALYSWP YHFLRKLGSD KGVFSFEAGR RCHSGEGLFA FSTPCAPDLC
RAVAGAIARQ RERLPELTRP QPCPLPRATS LPSLDTPGEL REMPPGPEPP TSRKMHLAEP
GPQSLPLLLG PEPNDLASGL YASVCKRASG PPGNEHLYEN LCVLEASPTL HGGEPEPHEG
PGSRSPTTSP IYHNGQDLSW PGPANDSTLE AQYRRLLELD QVEGTGRPDP QAGFKAKLVT
LLSRERRKGP APCDRP
Records:
Category Evidence Reference
A Mutagenesis Robson JD, Davidson D, Veillette A., Inhibition of the Jun N-terminal protein kinase pathway by SHIP-1, a lipid phosphatase that interacts with the adaptor molecule Dok-3, [14993273]
End of Record Details