ul_2502----
Record details: Hide
PPBD protein
Gene name CSK( Description: c-src tyrosine kinase. )
Synonyms C-SRC kinase; EC 2.7.10.2; MGC117393; Protein-tyrosine kinase CYL
GO annotations GO_component: cytoplasm [PMID 8890164]; plasma membrane [PMID 10790433]
GO_function:ATP binding; nucleotide binding; protein C-terminus binding [PMID 8890164]; protein-tyrosine kinase activity [PMID 1945408]; transferase activity
GO_process: intracellular signaling cascade; protein amino acid phosphorylation [PMID 1945408]; regulation of progression through cell cycle [PMID 1377109]
RefSeq accession NP_004374
SwissProt accession P41240
Substrate protein
Gene name Cbp( Description: Csk binding protein. )
Synonyms
GO annotations GO_component: extracellular space; integral to plasma membrane; membrane
GO_function:transmembrane receptor protein tyrosine kinase adaptor protein activity
GO_process: immune response; signal transduction
RefSeq accession NP_071589
SwissProt accession
Sequence:(RefSeq accession:NP_071589; substrate region highlighted if known)
1
61
121
181
241
301
361
421
MGPAGSALSS GQMQMQMVLW GSLAAVAMFF LITFLILLCS SCDRDKKPRQ HSGDHESLMN
VPSDKEMFSH SATSLTTDAL ASSEQNGVLT NGDILSEDST MTCMQHYEEV QTSASDLLDS
QDSTGKAKCH QSRELPRIPP ENAVDAMLTA RAADGDSGPG VEGPYEVLKD SSSQENMVED
CLYETVKEIK EVADKSQGGK SKSTSALKEL QGAHAEGKAD FAEYASVDRN KKCRHSTNAE
SILGTSSDLD EETPPPVPVK LLDENANLPE KGEHGAEEQA PEAPSGHSKR FSSLSYKSRE
EDPTLTEEEI SAMYSSVNKP GQSAHKPGPE STCQCPQGPP QRSSSSCNDL YATVKDFEKT
PNSISMLPPA RRPGEEPEPD YEAIQTLNRE DDKVPLGTNG HLVPKENDYE SIGDLQQGRD
VTRL
Records:
Category Evidence Reference
A Peptide library Lin X, Ayrapetov MK, Lee S, Parang K, Sun G., Probing the communication between the regulatory and catalytic domains of a protein tyrosine kinase, Csk, [15683240]
End of Record Details