ul_2520----
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PPBD protein
Gene name FES( Description: feline sarcoma oncogene. )
Synonyms C-Fes; EC 2.7.10.2; FPS
GO annotations GO_component:
GO_function:ATP binding; nucleotide binding; protein-tyrosine kinase activity [PMID 6183005]; transferase activity
GO_process: cell proliferation [PMID 6264598]; development [PMID 6264598]; intracellular signaling cascade; protein amino acid phosphorylation [PMID 6183005]
RefSeq accession NP_001996
SwissProt accession P07332
Substrate protein
Gene name Tec( Description: cytoplasmic tyrosine kinase, Dscr28C related (Drosophila). )
Synonyms
GO annotations GO_component:
GO_function:ATP binding; kinase activity; metal ion binding; nucleotide binding; protein binding; protein kinase activity; protein-tyrosine kinase activity; transferase activity; zinc ion binding
GO_process: intracellular signaling cascade; protein amino acid phosphorylation
RefSeq accession NP_038717
SwissProt accession
Sequence:(RefSeq accession:NP_038717; substrate region highlighted if known)
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MMVSFPVKIN FHSSPQSRDR WVKKLKEEIK NNNNIMIKYH PKFWADGSYQ CCRQTEKLAP
GCEKYNLFES SIRKTLPPAP EIKKRRPPPP IPPEEENTEE IVVAMYDFQA TEAHDLRLER
GQEYIILEKN DLHWWRARDK YGWYCRNTNR SKAEQLLRTE DKEGGFMVRD SSQPGLYTVS
LYTKFGGEGS SGFRHYHIKE TATSPKKYYL AEKHAFGSIP EIIEYHKHNA AGLVTRLRYP
VSTKGKNAPT TAGFSYDKWE INPSELTFMR ELGSGLFGVV RLGKWRAQYK VAIKAIREGA
MCEEDFIEEA KVMMKLTHPK LVQLYGVCTQ QKPIYIVTEF MERGCLLNFL RQRQGHFSRD
MLLSMCQDVC EGMEYLERNS FIHRDLAARN CLVNEAGVVK VSDFGMARYV LDDQYTSSSG
AKFPVKWCPP EVFNYSRFSS KSDVWSFGVL MWEIFTEGRM PFEKNTNYEV VTMVTRGHRL
HRPKLATKYL YEVMLRCWQE RPEGRPSFED LLRTIDELVE CEETFGR
Records:
Category Evidence Reference
A Inference Songyang Z, Shoelson SE, McGlade J, Olivier P, Pawson T, Bustelo XR, Barbacid M, Sabe H, Hanafusa H, Yi T, et al., Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav, [7511210]
End of Record Details