ul_2523----
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PPBD protein
Gene name FES( Description: feline sarcoma oncogene. )
Synonyms C-Fes; EC 2.7.10.2; FPS
GO annotations GO_component:
GO_function:ATP binding; nucleotide binding; protein-tyrosine kinase activity [PMID 6183005]; transferase activity
GO_process: cell proliferation [PMID 6264598]; development [PMID 6264598]; intracellular signaling cascade; protein amino acid phosphorylation [PMID 6183005]
RefSeq accession NP_001996
SwissProt accession P07332
Substrate protein
Gene name Clk1( Description: CDC-like kinase 1. )
Synonyms STY
GO annotations GO_component: nucleus
GO_function:ATP binding; kinase activity; nucleotide binding; protein kinase activity; protein serine/threonine kinase activity; protein-tyrosine kinase activity; transferase activity
GO_process: peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; peptidyl-tyrosine phosphorylation; protein amino acid autophosphorylation; protein amino acid phosphorylation
RefSeq accession NP_001036099
SwissProt accession
Sequence:(RefSeq accession:NP_001036099; substrate region highlighted if known)
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MRHSKRTYCP DWDERDWDYG TWRSSSSHKR KKRSHSSARE QKRCRYDHSK TTDSYYLESR
SINEKAYHSR RYVDEYRNDY MGYEPGHPYG EPGSRYQMHS SKSSGRSGRS SYKSKHRSRH
HTSQHHSHGK SHRRKRSRSV EDDEEGHLIC QSGDVLSARY EIVDTLGEGA FGKVVECIDH
KVGGRRVAVK IVKNVDRYCE AAQSEIQVLE HLNTTDPHST FRCVQMLEWF EHRGHICIVF
ELLGLSTYDF IKENSFLPFR MDHIRKMAYQ ICKSVNFLHS NKLTHTDLKP ENILFVKSDY
TEAYNPKMKR DERTIVNPDI KVVDFGSATY DDEHHSTLVS TRHYRAPEVI LALGWSQPCD
VWSIGCILIE YYLGFTVFPT HDSREHLAMM ERILGPLPKH MIQKTRKRRY FHHDRLDWDE
HSSAGRYVSR RCKPLKEFML SQDAEHELLF DLIGKMLEYD PAKRITLKEA LKHPFFYPLK
KHT
Records:
Category Evidence Reference
A Inference Songyang Z, Shoelson SE, McGlade J, Olivier P, Pawson T, Bustelo XR, Barbacid M, Sabe H, Hanafusa H, Yi T, et al., Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav, [7511210]
End of Record Details