ul_2530----
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PPBD protein
Gene name FES( Description: feline sarcoma oncogene. )
Synonyms C-Fes; EC 2.7.10.2; FPS
GO annotations GO_component:
GO_function:ATP binding; nucleotide binding; protein-tyrosine kinase activity [PMID 6183005]; transferase activity
GO_process: cell proliferation [PMID 6264598]; development [PMID 6264598]; intracellular signaling cascade; protein amino acid phosphorylation [PMID 6183005]
RefSeq accession NP_001996
SwissProt accession P07332
Substrate protein
Gene name Cd3e( Description: CD3 antigen, epsilon polypeptide. )
Synonyms AI504783; CD3; CD3epsilon; T3e
GO annotations GO_component: alpha-beta T cell receptor complex; external side of plasma membrane; immunological synapse; membrane; plasma membrane; T cell receptor complex
GO_function:protein binding; receptor activity; signal transducer activity; transmembrane receptor activity
GO_process: cell surface receptor linked signal transduction; lymphocyte activation; negative thymic T cell selection; positive regulation of calcium-mediated signaling; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of T cell proliferation; T cell receptor signaling pathway
RefSeq accession NP_031674
SwissProt accession
Sequence:(RefSeq accession:NP_031674; substrate region highlighted if known)
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61
121
181
MRWNTFWGIL CLSLLAVGTC QDDAENIEYK VSISGTSVEL TCPLDSDENL KWEKNGQELP
QKHDKHLVLQ DFSEVEDSGY YVCYTPASNK NTYLYLKARV CEYCVEVDLT AVAIIIIVDI
CITLGLLMVI YYWSKNRKAK AKPVTRGTGA GSRPRGQNKE RPPPVPNPDY EPIRKGQRDL
YSGLNQRAV
Records:
Category Evidence Reference
A Inference Songyang Z, Shoelson SE, McGlade J, Olivier P, Pawson T, Bustelo XR, Barbacid M, Sabe H, Hanafusa H, Yi T, et al., Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav, [7511210]
End of Record Details