ul_2531----
Record details: Hide
PPBD protein
Gene name FES( Description: feline sarcoma oncogene. )
Synonyms C-Fes; EC 2.7.10.2; FPS
GO annotations GO_component:
GO_function:ATP binding; nucleotide binding; protein-tyrosine kinase activity [PMID 6183005]; transferase activity
GO_process: cell proliferation [PMID 6264598]; development [PMID 6264598]; intracellular signaling cascade; protein amino acid phosphorylation [PMID 6183005]
RefSeq accession NP_001996
SwissProt accession P07332
Substrate protein
Gene name Fcgr1( Description: Fc receptor, IgG, high affinity I. )
Synonyms AI323638; AV092959; CD64; FcgammaRI; IGGHAFC
GO annotations GO_component: external side of plasma membrane; membrane
GO_function:IgG binding; IgG receptor activity; receptor activity
GO_process: antibody-dependent cellular cytotoxicity; antigen processing and presentation of exogenous antigen; antigen processing and presentation of exogenous peptide antigen via MHC class I; cell surface receptor linked signal transduction; defense response to bacterium; phagocytosis, engulfment; phagocytosis, recognition; positive regulation of phagocytosis; positive regulation of type IIa hypersensitivity; positive regulation of type III hypersensitivity; receptor mediated endocytosis; regulation of immune response
RefSeq accession NP_034316
SwissProt accession
Sequence:(RefSeq accession:NP_034316; substrate region highlighted if known)
1
61
121
181
241
301
361
MILTSFGDDM WLLTTLLLWV PVGGEVVNAT KAVITLQPPW VSIFQKENVT LWCEGPHLPG
DSSTQWFING TAVQISTPSY SIPEASFQDS GEYRCQIGSS MPSDPVQLQI HNDWLLLQAS
RRVLTEGEPL ALRCHGWKNK LVYNVVFYRN GKSFQFSSDS EVAILKTNLS HSGIYHCSGT
GRHRYTSAGV SITVKELFTT PVLRASVSSP FPEGSLVTLN CETNLLLQRP GLQLHFSFYV
GSKILEYRNT SSEYHIARAE REDAGFYWCE VATEDSSVLK RSPELELQVL GPQSSAPVWF
HILFYLSVGI MFSLNTVLYV KIHRLQREKK YNLEVPLVSE QGKKANSFQQ VRSDGVYEEV
TATASQTTPK EAPDGPRSSV GDCGPEQPEP LPPSDSTGAQ TSQS
Records:
Category Evidence Reference
A Inference Songyang Z, Shoelson SE, McGlade J, Olivier P, Pawson T, Bustelo XR, Barbacid M, Sabe H, Hanafusa H, Yi T, et al., Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav, [7511210]
End of Record Details