ul_2532----
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PPBD protein
Gene name FES( Description: feline sarcoma oncogene. )
Synonyms C-Fes; EC 2.7.10.2; FPS
GO annotations GO_component:
GO_function:ATP binding; nucleotide binding; protein-tyrosine kinase activity [PMID 6183005]; transferase activity
GO_process: cell proliferation [PMID 6264598]; development [PMID 6264598]; intracellular signaling cascade; protein amino acid phosphorylation [PMID 6183005]
RefSeq accession NP_001996
SwissProt accession P07332
Substrate protein
Gene name Csf3r( Description: colony stimulating factor 3 receptor (granulocyte). )
Synonyms Cd114; Csfgr; G-CSFR; MGC141472; MGC141473
GO annotations GO_component: membrane
GO_function:hematopoietin/interferon-class (D200-domain) cytokine receptor activity; protein binding; receptor activity
GO_process: cell adhesion; neutrophil chemotaxis
RefSeq accession NP_031808
SwissProt accession
Sequence:(RefSeq accession:NP_031808; substrate region highlighted if known)
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MVGLGACTLT GVTLIFLLLP RSLESCGHIE ISPPVVRLGD PVLASCTISP NCSKLDQQAK
ILWRLQDEPI QPGDRQHHLP DGTQESLITL PHLNYTQAFL FCLVPWEDSV QLLDQAELHA
GYPPASPSNL SCLMHLTTNS LVCQWEPGPE THLPTSFILK SFRSRADCQY QGDTIPDCVA
KKRQNNCSIP RKNLLLYQYM AIWVQAENML GSSESPKLCL DPMDVVKLEP PMLQALDIGP
DVVSHQPGCL WLSWKPWKPS EYMEQECELR YQPQLKGANW TLVFHLPSSK DQFELCGLHQ
APVYTLQMRC IRSSLPGFWS PWSPGLQLRP TMKAPTIRLD TWCQKKQLDP GTVSVQLFWK
PTPLQEDSGQ IQGYLLSWNS PDHQGQDIHL CNTTQLSCIF LLPSEAQNVT LVAYNKAGTS
SPTTVVFLEN EGPAVTGLHA MAQDLNTIWV DWEAPSLLPQ GYLIEWEMSS PSYNNSYKSW
MIEPNGNITG ILLKDNINPF QLYRITVAPL YPGIVGPPVN VYTFAGERAP PHAPALHLKH
VGTTWAQLEW VPEAPRLGMI PLTHYTIFWA DAGDHSFSVT LNISLHDFVL KHLEPASLYH
VYLMATSRAG STNSTGLTLR TLDPSDLNIF LGILCLVLLS TTCVVTWLCC KRRGKTSFWS
DVPDPAHSSL SSWLPTIMTE ETFQLPSFWD SSVPSITKIT ELEEDKKPTH WDSESSGNGS
LPALVQAYVL QGDPREISNQ SQPPSRTGDQ VLYGQVLESP TSPGVMQYIR SDSTQPLLGG
PTPSPKSYEN IWFHSRPQET FVPQPPNQED DCVFGPPFDF PLFQGLQVHG VEEQGGF
Records:
Category Evidence Reference
A Inference Songyang Z, Shoelson SE, McGlade J, Olivier P, Pawson T, Bustelo XR, Barbacid M, Sabe H, Hanafusa H, Yi T, et al., Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav, [7511210]
End of Record Details