ul_2537----
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PPBD protein
Gene name FES( Description: feline sarcoma oncogene. )
Synonyms C-Fes; EC 2.7.10.2; FPS
GO annotations GO_component:
GO_function:ATP binding; nucleotide binding; protein-tyrosine kinase activity [PMID 6183005]; transferase activity
GO_process: cell proliferation [PMID 6264598]; development [PMID 6264598]; intracellular signaling cascade; protein amino acid phosphorylation [PMID 6183005]
RefSeq accession NP_001996
SwissProt accession P07332
Substrate protein
Gene name Ap1g1( Description: adaptor protein complex AP-1, gamma 1 subunit. )
Synonyms AA409002; AU041323; AW551707; Adtg; D8Ertd374e
GO annotations GO_component: clathrin coat of trans-Golgi network vesicle; clathrin-coated vesicle; coated pit; Golgi trans face; perinuclear region
GO_function:binding; protein binding
GO_process: endocytosis; intracellular protein transport; protein complex assembly; protein transport; transport; vesicle-mediated transport
RefSeq accession NP_033807
SwissProt accession
Sequence:(RefSeq accession:NP_033807; substrate region highlighted if known)
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MPAPIRLREL IRTIRTARTQ AEEREMIQKE CAAIRSSFRE EDNTYRCRNV AKLLYMHMLG
YPAHFGQLEC LKLIASQKFT DKRIGYLGAM LLLDERQDVH LLMTNCIKND LNHSTQFVQG
LALCTLGCMG SSEMCRDLAG EVEKLLKTSN SYLRKKAALC AVHVIRKVPE LMEMFLPATK
NLLNEKNHGV LHTSVVLLTE MCERSPDMLA HFRKNEKLVP QLVRILKNLI MSGYSPEHDV
SGISDPFLQV RILRLLRILG RNDDDSSEAM NDILAQVATN TETSKNVGNA ILYETVLTIM
DIKSESGLRV LAINILGRFL LNNDKNIRYV ALTSLLKTVQ TDHNAVQRHR STIVDCLKDL
DVSIKRRAME LSFALVNGNN IRGMMKELLY FLDSCEPEFK ADCASGIFLA AEKYAPSKRW
HIDTIMRVLT TAGSYVRDDA VPNLIQLITN SVEMHAYTVQ RLYKAILGDY SQQPLVQVAA
WCIGEYGDLL VSGQCEEEEP IQVTEDEVLD ILESVLISNM STSVTRGYAL TAIMKLSTRF
TCTVNRIKKV VSIYGSSIDV ELQQRAVEYN ALFKKYDHMR SALLERMPVM EKVTTNGPSE
IVQTNGETEP APLETKPPPS GPQPTSQAND LLDLLGGNDI TPVIPTAPTS KPASAGGELL
DLLGDITLTG APAAAPTPAS VPQISQPPFL LDGLSSQPLF NDIAPGIPSI TAYSKNGLKI
EFTFERSNTN PSVTVITIQA SNSTELDMTD FVFQAAVPKT FQLQLLSPSS SVVPAFNTGT
ITQVIKVLNP QKQQLRMRIK LTYNHKGSAM QDLAEVNNFP PQSWQ
Records:
Category Evidence Reference
A Inference Songyang Z, Shoelson SE, McGlade J, Olivier P, Pawson T, Bustelo XR, Barbacid M, Sabe H, Hanafusa H, Yi T, et al., Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav, [7511210]
End of Record Details