ul_2539----
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PPBD protein
Gene name FES( Description: feline sarcoma oncogene. )
Synonyms C-Fes; EC 2.7.10.2; FPS
GO annotations GO_component:
GO_function:ATP binding; nucleotide binding; protein-tyrosine kinase activity [PMID 6183005]; transferase activity
GO_process: cell proliferation [PMID 6264598]; development [PMID 6264598]; intracellular signaling cascade; protein amino acid phosphorylation [PMID 6183005]
RefSeq accession NP_001996
SwissProt accession P07332
Substrate protein
Gene name MS4A2( Description: membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide). )
Synonyms APY; ATOPY; FCER1B; FCERI; Fc epsilon receptor I beta-chain; FcERI; IGEL; IGER; IGHER; IgE Fc receptor subunit beta; MS4A1; Membrane-spanning 4-domains subfamily A member 2
GO annotations GO_component: integral to plasma membrane [PMID 2448768]; membrane
GO_function:calcium channel activity [PMID 9169438]; IgE binding; receptor activity
GO_process: cell proliferation [PMID 2448768]; G-protein coupled receptor protein signaling pathway [PMID 9169438]; humoral immune response [PMID 2448768]; signal transduction
RefSeq accession NP_000130
SwissProt accession Q01362
GO Pathway:
GO:0004872     receptor activity
Sequence:(RefSeq accession:NP_000130; substrate region highlighted if known)
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MDTESNRRAN LALPQEPSSV PAFEVLEISP QEVSSGRLLK SASSPPLHTW LTVLKKEQEF
LGVTQILTAM ICLCFGTVVC SVLDISHIEG DIFSSFKAGY PFWGAIFFSI SGMLSIISER
RNATYLVRGS LGANTASSIA GGTGITILII NLKKSLAYIH IHSCQKFFET KCFMASFSTE
IVVMMLFLTI LGLGSAVSLT ICGAGEELKG NKVPEDRVYE ELNIYSATYS ELEDPGEMSP
PIDL
Records:
Category Evidence Reference
A Inference Jouvin MH, Numerof RP, Kinet JP., Signal transduction through the conserved motifs of the high affinity IgE receptor Fc epsilon RI, [7612892]
End of Record Details