ul_2557----
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PPBD protein
Gene name FGR( Description: Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog. )
Synonyms C-FGR; EC 2.7.10.2; FLJ43153; MGC75096; P55-FGR; SRC2; c-fgr; c-src2; p55c-fgr; p58c-fgr
GO annotations GO_component:
GO_function:ATP binding; nucleotide binding; protein-tyrosine kinase activity [PMID 3003578]; transferase activity
GO_process: intracellular signaling cascade; protein amino acid phosphorylation [PMID 2995972]; response to virus [PMID 3003578]
RefSeq accession NP_001036212
SwissProt accession P09769
Substrate protein
Gene name Pdgfrb( Description: platelet derived growth factor receptor, beta polypeptide. )
Synonyms AI528809; CD140b; Pdgfr
GO annotations GO_component: membrane
GO_function:ATP binding; kinase activity; nucleotide binding; protein kinase activity; protein-tyrosine kinase activity; receptor activity; signal transducer activity; transferase activity; transmembrane receptor protein tyrosine kinase activity; vascular endothelial growth factor receptor activity
GO_process: protein amino acid phosphorylation; regulation of peptidyl-tyrosine phosphorylation; signal transduction; transmembrane receptor protein tyrosine kinase signaling pathway
RefSeq accession NP_032835
SwissProt accession
Sequence:(RefSeq accession:NP_032835; substrate region highlighted if known)
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MGLPGVIPAL VLRGQLLLSV LWLLGPQTSR GLVITPPGPE FVLNISSTFV LTCSGSAPVM
WEQMSQVPWQ EAAMNQDGTF SSVLTLTNVT GGDTGEYFCV YNNSLGPELS ERKRIYIFVP
DPTMGFLPMD SEDLFIFVTD VTETTIPCRV TDPQLEVTLH EKKVDIPLHV PYDHQRGFTG
TFEDKTYICK TTIGDREVDS DTYYVYSLQV SSINVSVNAV QTVVRQGESI TIRCIVMGND
VVNFQWTYPR MKSGRLVEPV TDYLFGVPSR IGSILHIPTA ELSDSGTYTC NVSVSVNDHG
DEKAINISVI ENGYVRLLET LGDVEIAELH RSRTLRVVFE AYPMPSVLWL KDNRTLGDSG
AGELVLSTRN MSETRYVSEL ILVRVKVSEA GYYTMRAFHE DDEVQLSFKL QVNVPVRVLE
LSESHPANGE QTIRCRGRGM PQPNVTWSTC RDLKRCPRKL SPTPLGNSSK EESQLETNVT
FWEEDQEYEV VSTLRLRHVD QPLSVRCMLQ NSMGGDSQEV TVVPHSLPFK VVVISAILAL
VVLTVISLII LIMLWQKKPR YEIRWKVIES VSSDGHEYIY VDPVQLPYDS TWELPRDQLV
LGRTLGSGAF GQVVEATAHG LSHSQATMKV AVKMLKSTAR SSEKQALMSE LKIMSHLGPH
LNVVNLLGAC TKGGPIYIIT EYCRYGDLVD YLHRNKHTFL QRHSNKHCPP SAELYSNALP
VGFSLPSHLN LTGESDGGYM DMSKDESIDY VPMLDMKGDI KYADIESPSY MAPYDNYVPS
APERTYRATL INDSPVLSYT DLVGFSYQVA NGMDFLASKN CVHRDLAARN VLICEGKLVK
ICDFGLARDI MRDSNYISKG STYLPLKWMA PESIFNSLYT TLSDVWSFGI LLWEIFTLGG
TPYPELPMND QFYNAIKRGY RMAQPAHASD EIYEIMQKCW EEKFETRPPF SQLVLLLERL
LGEGYKKKYQ QVDEEFLRSD HPAILRSQAR FPGIHSLRSP LDTSSVLYTA VQPNESDNDY
IIPLPDPKPD VADEGLPEGS PSLASSTLNE VNTSSTISCD SPLELQEEPQ QAEPEAQLEQ
PQDSGCPGPL AEAEDSFL
Records:
Category Evidence Reference
A Inference Songyang Z, Shoelson SE, Chaudhuri M, Gish G, Pawson T, Haser WG, King F, Roberts T, Ratnofsky S, Lechleider RJ, et al., SH2 domains recognize specific phosphopeptide sequences, [7680959]
End of Record Details