ul_2650----
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PPBD protein
Gene name FYN( Description: FYN oncogene related to SRC, FGR, YES. )
Synonyms EC 2.7.10.2; MGC45350; Protooncogene Syn; SLK; SYN; p59-Fyn
GO annotations GO_component:
GO_function:ATP binding; identical protein binding [PMID 14993658]; non-membrane spanning protein tyrosine kinase activity [PMID 7822789]; nucleotide binding; protein binding [PMID 10790433]; protein-tyrosine kinase activity [PMID 1361685]; transferase activity
GO_process: calcium ion transport [PMID 7822789]; feeding behavior [PMID 8264796]; intracellular signaling cascade; learning [PMID 1361685]; protein amino acid phosphorylation [PMID 3526330] [PMID 7822789]; protein kinase cascade [PMID 1361685]; T cell receptor signaling pathway [PMID 7722293]
RefSeq accession NP_002028
SwissProt accession P06241
Substrate protein
Gene name FAS
Synonyms Apo-1 antigen; Apoptosis-mediating surface antigen FAS; CD95 antigen; FASLG receptor
GO annotations GO_component: cytosol [PMID 7533181]; integral to membrane; membrane; soluble fraction [PMID 7510905]
GO_function:identical protein binding [PMID 7536190]; protein binding; transmembrane receptor activity
GO_process: anti-apoptosis [PMID 7510905]; apoptosis; immune response; induction of apoptosis [PMID 1375228]; protein complex assembly [PMID 10875918]; regulation of apoptosis [PMID 7533181]; signal transduction [PMID 9360929]
RefSeq accession NP_000034
SwissProt accession P25445
Sequence:(RefSeq accession:NP_000034; substrate region highlighted if known)
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MLGIWTLLPL VLTSVARLSS KSVNAQVTDI NSKGLELRKT VTTVETQNLE GLHHDGQFCH
KPCPPGERKA RDCTVNGDEP DCVPCQEGKE YTDKAHFSSK CRRCRLCDEG HGLEVEINCT
RTQNTKCRCK PNFFCNSTVC EHCDPCTKCE HGIIKECTLT SNTKCKEEGS RSNLGWLCLL
LLPIPLIVWV KRKEVQKTCR KHRKENQGSH ESPTLNPETV AINLSDVDLS KYITTIAGVM
TLSQVKGFVR KNGVNEAKID EIKNDNVQDT AEQKVQLLRN WHQLHGKKEA YDTLIKDLKK
ANLCTLAEKI QTIILKDITS DSENSNFRNE IQSLV
Records:
Category Evidence Reference
A Inference Atkinson EA, Ostergaard H, Kane K, Pinkoski MJ, Caputo A, Olszowy MW, Bleackley RC., A physical interaction between the cell death protein Fas and the tyrosine kinase p59fynT, [8626376]
End of Record Details