ul_2694----
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PPBD protein
Gene name FYN( Description: FYN oncogene related to SRC, FGR, YES. )
Synonyms EC 2.7.10.2; MGC45350; Protooncogene Syn; SLK; SYN; p59-Fyn
GO annotations GO_component:
GO_function:ATP binding; identical protein binding [PMID 14993658]; non-membrane spanning protein tyrosine kinase activity [PMID 7822789]; nucleotide binding; protein binding [PMID 10790433]; protein-tyrosine kinase activity [PMID 1361685]; transferase activity
GO_process: calcium ion transport [PMID 7822789]; feeding behavior [PMID 8264796]; intracellular signaling cascade; learning [PMID 1361685]; protein amino acid phosphorylation [PMID 3526330] [PMID 7822789]; protein kinase cascade [PMID 1361685]; T cell receptor signaling pathway [PMID 7722293]
RefSeq accession NP_002028
SwissProt accession P06241
Substrate protein
Gene name CTLA4( Description: cytotoxic T-lymphocyte-associated protein 4. )
Synonyms CD152; CD152 antigen; CELIAC3; CTLA-4; Cytotoxic T-lymphocyte-associated antigen 4; GSE; IDDM12
GO annotations GO_component: integral to plasma membrane [PMID 3220103]; membrane
GO_function:
GO_process: immune response [PMID 3220103]
RefSeq accession NP_005205
SwissProt accession P16410
GO Pathway:
GO:0007242     intracellular signaling cascade
Sequence:(RefSeq accession:NP_005205; substrate region highlighted if known)
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MACLGFQRHK AQLNLATRTW PCTLLFFLLF IPVFCKAMHV AQPAVVLASS RGIASFVCEY
ASPGKATEVR VTVLRQADSQ VTEVCAATYM MGNELTFLDD SICTGTSSGN QVNLTIQGLR
AMDTGLYICK VELMYPPPYY LGIGNGTQIY VIDPEPCPDS DFLLWILAAV SSGLFFYSFL
LTAVSLSKML KKRSPLTTGV YVKMPPTEPE CEKQFQPYFI PIN
Records:
Category Evidence Reference
A Inference Miyatake S, Nakaseko C, Umemori H, Yamamoto T, Saito T., Src family tyrosine kinases associate with and phosphorylate CTLA-4 (CD152), [9712716]
End of Record Details