ul_27----
Record details: Hide
PPBD protein
Gene name SFN( Description: stratifin. )
Synonyms Epithelial cell marker protein 1; Stratifin; YWHAS
GO annotations GO_component: cytoplasm [PMID 10767298]; extracellular space [PMID 8515476]
GO_function:protein domain specific binding; protein kinase C inhibitor activity [PMID 8515476]
GO_process: cell proliferation [PMID 10767298]; negative regulation of protein kinase activity [PMID 8515476]; regulation of progression through cell cycle [PMID 10767298]; signal transduction [PMID 8515476]
RefSeq accession NP_006133
SwissProt accession P31947
Substrate protein
Gene name Wwtr1( Description: WW domain containing transcription regulator 1. )
Synonyms 2310058J06Rik; 2610021I22Rik; C78399; TAZ
GO annotations GO_component: cytoplasm; nucleus; transcription factor complex
GO_function:protein binding; transcription coactivator activity; transcription corepressor activity; transcription regulator activity
GO_process: negative regulation of fat cell differentiation; negative regulation of transcription from RNA polymerase II promoter; osteoblast differentiation; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; transcription
RefSeq accession NP_598545
SwissProt accession Q9EPK5
Sequence:(RefSeq accession:NP_598545; substrate region highlighted if known)
1
61
121
181
241
301
361
MNPSSVPHPL PPPGQQVIHV TQDLDTDLEA LFNSVMNPKP SSWRKKILPE SFFKEPDSGS
HSRQSSTDSS GGHPGPRLAG GAQHVRSHSS PASLQLGTGA GAAGGPAQQH AHLRQQSYDV
TDELPLPPGW EMTFTATGQR YFLNHIEKIT TWQDPRKVMN QPLNHVNLHP SITSTSVPQR
SMAVSQPNLA MNHQHQQVVA TSLSPQNHPT QNQPTGLMSV PNALTTQQQQ QQKLRLQRIQ
MERERIRMRQ EELMRQEAAL CRQLPMETET MAPVNTPAMS TDMRSVTNSS SDPFLNGGPY
HSREQSTDSG LGLGCYSVPT TPEDFLSNMD EMDTGENSGQ TPMTVNPQQT RFPDFLDCLP
GTNVDLGTLE SEDLIPLFND VESALNKSEP FLTWL
Records:
Category Evidence Reference
A Mutagenesis Kanai F, Marignani PA, Sarbassova D, Yagi R, Hall RA, Donowitz M, Hisaminato A, Fujiwara T, Ito Y, Cantley LC, Yaffe MB., TAZ: a novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ domain proteins., [11118213]
End of Record Details