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Record details: Hide
PPBD protein
Gene name YWHAB( Description: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide. )
Synonyms GW128; HS1; KCIP-1; Protein 1054; Protein kinase C inhibitor protein 1
GO annotations GO_component: cytoplasm [PMID 12963375]; perinuclear region [PMID 12963375]
GO_function:monooxygenase activity; protein domain specific binding
GO_process:
RefSeq accession NP_003395
SwissProt accession P31946
Substrate protein
Gene name CTNNB1( Description: catenin (cadherin-associated protein), beta 1, 88kDa. )
Synonyms CTNNB; DKFZp686D02253; FLJ25606; FLJ37923
GO annotations GO_component: cytoskeleton [PMID 7806582]; intercellular junction; lateral plasma membrane [PMID 12072559]; nucleus [PMID 9065401]; plasma membrane [PMID 10837025]
GO_function:androgen receptor binding [PMID 15572661]; protein binding [PMID 11590244]; signal transducer activity [PMID 10192393]; structural molecule activity; transcription coactivator activity [PMID 15572661]
GO_process: androgen receptor signaling pathway [PMID 15572661]; cell adhesion; positive regulation of transcription, DNA-dependent [PMID 15572661]; regulation of transcription from RNA polymerase II promoter; transcription; Wnt receptor signaling pathway
RefSeq accession NP_001895
SwissProt accession P35222
GO Pathway:
GO:0006605     protein targeting
Sequence:(RefSeq accession:NP_001895; substrate region highlighted if known)
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MATQADLMEL DMAMEPDRKA AVSHWQQQSY LDSGIHSGAT TTAPSLSGKG NPEEEDVDTS
QVLYEWEQGF SQSFTQEQVA DIDGQYAMTR AQRVRAAMFP ETLDEGMQIP STQFDAAHPT
NVQRLAEPSQ MLKHAVVNLI NYQDDAELAT RAIPELTKLL NDEDQVVVNK AAVMVHQLSK
KEASRHAIMR SPQMVSAIVR TMQNTNDVET ARCTAGTLHN LSHHREGLLA IFKSGGIPAL
VKMLGSPVDS VLFYAITTLH NLLLHQEGAK MAVRLAGGLQ KMVALLNKTN VKFLAITTDC
LQILAYGNQE SKLIILASGG PQALVNIMRT YTYEKLLWTT SRVLKVLSVC SSNKPAIVEA
GGMQALGLHL TDPSQRLVQN CLWTLRNLSD AATKQEGMEG LLGTLVQLLG SDDINVVTCA
AGILSNLTCN NYKNKMMVCQ VGGIEALVRT VLRAGDREDI TEPAICALRH LTSRHQEAEM
AQNAVRLHYG LPVVVKLLHP PSHWPLIKAT VGLIRNLALC PANHAPLREQ GAIPRLVQLL
VRAHQDTQRR TSMGGTQQQF VEGVRMEEIV EGCTGALHIL ARDVHNRIVI RGLNTIPLFV
QLLYSPIENI QRVAAGVLCE LAQDKEAAEA IEAEGATAPL TELLHSRNEG VATYAAAVLF
RMSEDKPQDY KKRLSVELTS SLFRTEPMAW NETADLGLDI GAQGEPLGYR QDDPSYRSFH
SGGYGQDALG MDPMMEHEMG GHHPGADYPV DGLPDLGHAQ DLMDGLPPGD SNQLAWFDTD
L
Records:
Category Evidence Reference
A Mutagenesis Fang D, Hawke D, Zheng Y, Xia Y, Meisenhelder J, Nika H, Mills GB, Kobayashi R, Hunter T, Lu Z., Phosphorylation of beta-catenin by AKT promotes beta-catenin transcriptional activity., [17287208]
End of Record Details