ul_2769----
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PPBD protein
Gene name FYN( Description: FYN oncogene related to SRC, FGR, YES. )
Synonyms EC 2.7.10.2; MGC45350; Protooncogene Syn; SLK; SYN; p59-Fyn
GO annotations GO_component:
GO_function:ATP binding; identical protein binding [PMID 14993658]; non-membrane spanning protein tyrosine kinase activity [PMID 7822789]; nucleotide binding; protein binding [PMID 10790433]; protein-tyrosine kinase activity [PMID 1361685]; transferase activity
GO_process: calcium ion transport [PMID 7822789]; feeding behavior [PMID 8264796]; intracellular signaling cascade; learning [PMID 1361685]; protein amino acid phosphorylation [PMID 3526330] [PMID 7822789]; protein kinase cascade [PMID 1361685]; T cell receptor signaling pathway [PMID 7722293]
RefSeq accession NP_002028
SwissProt accession P06241
Substrate protein
Gene name CCNA1( Description: cyclin A1. )
Synonyms
GO annotations GO_component: cytosol [PMID 9041194]; microtubule cytoskeleton [PMID 11256614]; nucleus
GO_function:protein binding [PMID 15232106]
GO_process: cell cycle; cell division; male meiosis I [PMID 9843212]; meiosis; mitosis; regulation of cyclin-dependent protein kinase activity; spermatogenesis [PMID 9843212]
RefSeq accession NP_003905
SwissProt accession P78396
Sequence:(RefSeq accession:NP_003905; substrate region highlighted if known)
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METGFPAIMY PGSFIGGWGE EYLSWEGPGL PDFVFQQQPV ESEAMHCSNP KSGVVLATVA
RGPDACQILT RAPLGQDPPQ RTVLGLLTAN GQYRRTCGQG ITRIRCYSGS ENAFPPAGKK
ALPDCGVQEP PKQGFDIYMD ELEQGDRDSC SVREGMAFED VYEVDTGTLK SDLHFLLDFN
TVSPMLVDSS LLSQSEDISS LGTDVINVTE YAEEIYQYLR EAEIRHRPKA HYMKKQPDIT
EGMRTILVDW LVEVGEEYKL RAETLYLAVN FLDRFLSCMS VLRGKLQLVG TAAMLLASKY
EEIYPPEVDE FVYITDDTYT KRQLLKMEHL LLKVLAFDLT VPTTNQFLLQ YLRRQGVCVR
TENLAKYVAE LSLLEADPFL KYLPSLIAAA AFCLANYTVN KHFWPETLAA FTGYSLSEIV
PCLSELHKAY LDIPHRPQQA IREKYKASKY LCVSLMEPPA VLLLQ
Records:
Category Evidence Reference
A Peptide affinity isolation Yaoi T, Chamnongpol S, Jiang X, Li X., Src homology 2 domain-based high throughput assays for profiling downstream molecules in receptor tyrosine kinase pathways, [16477079]
End of Record Details