ul_285----
Record details: Hide
PPBD protein
Gene name YWHAE( Description: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide. )
Synonyms 14-3-3E; FLJ45465; KCIP-1; MDCR; MDS
GO annotations GO_component:
GO_function:enzyme binding [PMID 10788521]; protein domain specific binding
GO_process:
RefSeq accession NP_006752
SwissProt accession P62258
Substrate protein
Gene name MAP3K10( Description: mitogen-activated protein kinase kinase kinase 10. )
Synonyms EC 2.7.11.25; MLK2; MST; Mixed lineage kinase 2; Protein kinase MST
GO annotations GO_component:
GO_function:ATP binding; JUN kinase kinase kinase activity; nucleotide binding; protein homodimerization activity [PMID 8195146]; protein serine/threonine kinase activity [PMID 8195146]; protein-tyrosine kinase activity; transferase activity
GO_process: activation of JNK activity [PMID 8195146]; induction of apoptosis [PMID 10801775]; protein amino acid autophosphorylation [PMID 8195146]; signal transduction [PMID 10801775]
RefSeq accession NP_002437
SwissProt accession Q02779
Sequence:(RefSeq accession:NP_002437; substrate region highlighted if known)
1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
MEEEEGAVAK EWGTTPAGPV WTAVFDYEAA GDEELTLRRG DRVQVLSQDC AVSGDEGWWT
GQLPSGRVGV FPSNYVAPGA PAAPAGLQLP QEIPFHELQL EEIIGVGGFG KVYRALWRGE
EVAVKAARLD PEKDPAVTAE QVCQEARLFG ALQHPNIIAL RGACLNPPHL CLVMEYARGG
ALSRVLAGRR VPPHVLVNWA VQVARGMNYL HNDAPVPIIH RDLKSINILI LEAIENHNLA
DTVLKITDFG LAREWHKTTK MSAAGTYAWM APEVIRLSLF SKSSDVWSFG VLLWELLTGE
VPYREIDALA VAYGVAMNKL TLPIPSTCPE PFARLLEECW DPDPHGRPDF GSILKRLEVI
EQSALFQMPL ESFHSLQEDW KLEIQHMFDD LRTKEKELRS REEELLRAAQ EQRFQEEQLR
RREQELAERE MDIVERELHL LMCQLSQEKP RVRKRKGNFK RSRLLKLREG GSHISLPSGF
EHKITVQASP TLDKRKGSDG ASPPASPSII PRLRAIRLTP VDCGGSSSGS SSGGSGTWSR
GGPPKKEELV GGKKKGRTWG PSSTLQKERV GGEERLKGLG EGSKQWSSSA PNLGKSPKHT
PIAPGFASLN EMEEFAEAED GGSSVPPSPY STPSYLSVPL PAEPSPGARA PWEPTPSAPP
ARWGHGARRR CDLALLGCAT LLGAVGLGAD VAEARAADGE EQRRWLDGLF FPRAGRFPRG
LSPPARPHGR REDVGPGLGL APSATLVSLS SVSDCNSTRS LLRSDSDEAA PAAPSPPPSP
PAPTPTPSPS TNPLVDLELE SFKKDPRQSL TPTHVTAACA VSRGHRRTPS DGALGQRGPP
EPAGHGPGPR DLLDFPRLPD PQALFPARRR PPEFPGRPTT LTFAPRPRPA ASRPRLDPWK
LVSFGRTLTI SPPSRPDTPE SPGPPSVQPT LLDMDMEGQN QDSTVPLCGA HGSH
Records:
Category Evidence Reference
A Inference Nagata K, Puls A, Futter C, Aspenstrom P, Schaefer E, Nakata T, Hirokawa N, Hall A., The MAP kinase kinase kinase MLK2 co-localizes with activated JNK along microtubules and associates with kinesin superfamily motor KIF3., [9427749]
End of Record Details