ul_3289----
Record details: Hide
PPBD protein
Gene name GRB2
Synonyms Adapter protein GRB2; Protein Ash; SH2/SH3 adapter GRB2
GO annotations GO_component: cytosol [PMID 14722116]
GO_function:epidermal growth factor receptor binding [PMID 12577067]; insulin receptor substrate binding [PMID 8388384]; SH3/SH2 adaptor activity [PMID 8253073]
GO_process: cell-cell signaling [PMID 8253073]; epidermal growth factor receptor signaling pathway [PMID 1322798]; insulin receptor signaling pathway [PMID 8388384]; intracellular signaling cascade; Ras protein signal transduction [PMID 8253073]
RefSeq accession NP_002077
SwissProt accession P62993
Substrate protein
Gene name C6orf21
Synonyms
GO annotations GO_component:
GO_function:
GO_process:
RefSeq accession NP_001003693
SwissProt accession O95869
GO Pathway:
GO:0007265     Ras protein signal transduction
Sequence:(RefSeq accession:NP_001003693; substrate region highlighted if known)
1
61
121
181
241
MAVLFLLLFL CGTPQAADNM QAIYVALGEA VELPCPSPPT LHGDEHLSWF CSPAAGSFTT
LVAQVQVGRP APDPGKPGRE SRLRLLGNYS LWLEGSKEED AGRYWCAVLG QHHNYQNWRV
YDVLVLKGSQ LSARAADGSP CNVLLCSVVP SRRMDSVTWQ EGKGPVRGRV QSFWGSEAAL
LLVCPGEGLS EPRSRRPRII RCLMTHNKGV SFSLAASIDA SPALCAPSTG WDMPWILMLL
LTMGQGVVIL ALSIVLWRQR VRGAPGRDAS IPQFKPEIQV YENIHLARLG PPAHKPR
Records:
Category Evidence Reference
A Mutagenesis De Vet EC, Aguado B, Campbell RD., Adaptor signalling proteins Grb2 and Grb7 are recruited by human G6f, a novel member of the immunoglobulin superfamily encoded in the MHC, [12852788]
End of Record Details