ul_3295----
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PPBD protein
Gene name GRB2
Synonyms
GO annotations GO_component: cytosol [PMID 14722116]
GO_function:epidermal growth factor receptor binding [PMID 12577067]; insulin receptor substrate binding [PMID 8388384]; SH3/SH2 adaptor activity [PMID 8253073]
GO_process: cell-cell signaling [PMID 8253073]; epidermal growth factor receptor signaling pathway [PMID 1322798]; insulin receptor signaling pathway [PMID 8388384]; intracellular signaling cascade; Ras protein signal transduction [PMID 8253073]
RefSeq accession NP_002077
SwissProt accession P29354
Substrate protein
Gene name Btla( Description: B and T lymphocyte associated. )
Synonyms A630002H24; MGC124217; MGC124218
GO annotations GO_component: integral to membrane; integral to plasma membrane; membrane
GO_function:protein binding; receptor activity
GO_process: immune response; negative regulation of B cell proliferation; negative regulation of T cell proliferation
RefSeq accession NP_001032808
SwissProt accession
Sequence:(RefSeq accession:NP_001032808; substrate region highlighted if known)
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MKTVPAMLGT PRLFREFFIL HLGLWSILCE KATKRNDEEC PVQLTITRNS KQSARTGELF
KIQCPVKYCV HRPNVTWCKH NGTICVPLEV SPQLYTSWEE NQSVPVFVLH FKPIHLSDNG
SYSCSTNFNS QVINSHSVTI HVTERTQNSS EHPLITVSDI PDATNASGPS TMEERPGRTW
LLYTLLPLGA LLLLLACVCL LCFLKRIQGK EKKPSDLAGR DTNLVDIPAS SRTNHQALPS
GTGIYDNDPW SSMQDESELT ISLQSERNNQ GIVYASLNHC VIGRNPRQEN NMQEAPTEYA
SICVRS
Records:
Category Evidence Reference
A Inference Gavrieli M, Watanabe N, Loftin SK, Murphy TL, Murphy KM., Characterization of phosphotyrosine binding motifs in the cytoplasmic domain of B and T lymphocyte attenuator required for association with protein tyrosine phosphatases SHP-1 and SHP-2, [14652006]
End of Record Details