ul_3296----
Record details: Hide
PPBD protein
Gene name GRB2
Synonyms
GO annotations GO_component: cytosol [PMID 14722116]
GO_function:epidermal growth factor receptor binding [PMID 12577067]; insulin receptor substrate binding [PMID 8388384]; SH3/SH2 adaptor activity [PMID 8253073]
GO_process: cell-cell signaling [PMID 8253073]; epidermal growth factor receptor signaling pathway [PMID 1322798]; insulin receptor signaling pathway [PMID 8388384]; intracellular signaling cascade; Ras protein signal transduction [PMID 8253073]
RefSeq accession NP_002077
SwissProt accession P29354
Substrate protein
Gene name BTLA( Description: B and T lymphocyte associated. )
Synonyms B- and T-lymphocyte-associated protein; BTLA1; CD272; CD272 antigen; FLJ16065; MGC129743
GO annotations GO_component: integral to membrane; membrane
GO_function:receptor activity
GO_process: immune response
RefSeq accession NP_861445
SwissProt accession Q7Z6A9
Sequence:(RefSeq accession:NP_861445; substrate region highlighted if known)
1
61
121
181
241
MKTLPAMLGT GKLFWVFFLI PYLDIWNIHG KESCDVQLYI KRQSEHSILA GDPFELECPV
KYCANRPHVT WCKLNGTTCV KLEDRQTSWK EEKNISFFIL HFEPVLPNDN GSYRCSANFQ
SNLIESHSTT LYVTDVKSAS ERPSKDEMAS RPWLLYSLLP LGGLPLLITT CFCLFCCLRR
HQGKQNELSD TAGREINLVD AHLKSEQTEA STRQNSQVLL SETGIYDNDP DLCFRMQEGS
EVYSNPCLEE NKPGIVYASL NHSVIGLNSR LARNVKEAPT EYASICVRS
Records:
Category Evidence Reference
A Inference Gavrieli M, Watanabe N, Loftin SK, Murphy TL, Murphy KM., Characterization of phosphotyrosine binding motifs in the cytoplasmic domain of B and T lymphocyte attenuator required for association with protein tyrosine phosphatases SHP-1 and SHP-2, [14652006]
End of Record Details