ul_3323----
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PPBD protein
Gene name GRB2
Synonyms
GO annotations GO_component: cytosol [PMID 14722116]
GO_function:epidermal growth factor receptor binding [PMID 12577067]; insulin receptor substrate binding [PMID 8388384]; SH3/SH2 adaptor activity [PMID 8253073]
GO_process: cell-cell signaling [PMID 8253073]; epidermal growth factor receptor signaling pathway [PMID 1322798]; insulin receptor signaling pathway [PMID 8388384]; intracellular signaling cascade; Ras protein signal transduction [PMID 8253073]
RefSeq accession NP_987102
SwissProt accession P29354
Substrate protein
Gene name MYO1C( Description: myosin IB. )
Synonyms MMI-beta; MMIb; Myosin I beta; myr1
GO annotations GO_component: myosin; unconventional myosin [PMID 9119401]
GO_function:actin binding; ATP binding; calmodulin binding; motor activity; nucleotide binding
GO_process:
RefSeq accession NP_203693
SwissProt accession O00159
Sequence:(RefSeq accession:NP_203693; substrate region highlighted if known)
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MESALTARDR VGVQDFVLLE NFTSEAAFIE NLRRRFRENL IYTYIGPVLV SVNPYRDLQI
YSRQHMERYR GVSFYEVPPH LFAVADTVYR ALRTERRDQA VMISGESGAG KTEATKRLLQ
FYAETCPAPE RGGAVRDRLL QSNPVLEAFG NAKTLRNDNS SRFGKYMDVQ FDFKGAPVGG
HILSYLLEKS RVVHQNHGER NFHIFYQLLE GGEEETLRRL GLERNPQSYL YLVKGQCAKV
SSINDKSDWK VVRKALTVID FTEDEVEDLL SIVASVLHLG NIHFAANEES NAQVTTENQL
KYLTRLLSVE GSTLREALTH RKIIAKGEEL LSPLNLEQAA YARDALAKAV YSRTFTWLVG
KINRSLASKD VESPSWRSTT VLGLLDIYGF EVFQHNSFEQ FCINYCNEKL QQLFIELTLK
SEQEEYEAEG IAWEPVQYFN NKIICDLVEE KFKGIISILD EECLRPGEAT DLTFLEKLED
TVKHHPHFLT HKLADQRTRK SLGRGEFRLL HYAGEVTYSV TGFLDKNNDL LFRNLKETMC
SSKNPIMSQC FDRSELSDKK RPETVATQFK MSLLQLVEIL QSKEPAYVRC IKPNDAKQPG
RFDEVLIRHQ VKYLGLLENL RVRRAGFAYR RKYEAFLQRY KSLCPETWPT WAGRPQDGVA
VLVRHLGYKP EEYKMGRTKI FIRFPKTLFA TEDALEVRRQ SLATKIQAAW RGFHWRQKFL
RVKRSAICIQ SWWRGTLGRR KAAKRKWAAQ TIRRLIRGFI LRHAPRCPEN AFFLDHVRTS
FLLNLRRQLP RNVLDTSWPT PPPALREASE LLRELCIKNM VWKYCRSISP EWKQQLQQKA
VASEIFKGKK DNYPQSVPRL FISTRLGTDE ISPRVLQALG SEPIQYAVPV VKYDRKGYKP
RSRQLLLTPN AVVIVEDAKV KQRIDYANLT GISVSSLSDS LFVLHVQRAD NKQKGDVVLQ
SDHVIETLTK TALSANRVNS ININQGSITF AGGPGRDGTI DFTPGSELLI TKAKNGHLAV
VAPRLNSR
Records:
Category Evidence Reference
A Inference McLaughlin WA, Hou T, Wang W., Prediction of binding sites of peptide recognition domains: an application on Grb2 and SAP SH2 domains, [16476443]
End of Record Details