ul_3344----
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PPBD protein
Gene name GRB2
Synonyms
GO annotations GO_component: cytosol [PMID 14722116]
GO_function:epidermal growth factor receptor binding [PMID 12577067]; insulin receptor substrate binding [PMID 8388384]; SH3/SH2 adaptor activity [PMID 8253073]
GO_process: cell-cell signaling [PMID 8253073]; epidermal growth factor receptor signaling pathway [PMID 1322798]; insulin receptor signaling pathway [PMID 8388384]; intracellular signaling cascade; Ras protein signal transduction [PMID 8253073]
RefSeq accession NP_987102
SwissProt accession P29354
Substrate protein
Gene name IL1RL1
Synonyms
GO annotations GO_component: integral to membrane; membrane
GO_function:interleukin-1 receptor activity; protein binding [PMID 8621446]; receptor signaling protein activity [PMID 1482686]; transmembrane receptor activity
GO_process: immune response [PMID 10527832]; signal transduction [PMID 1482686]
RefSeq accession NP_057316
SwissProt accession Q01638
Sequence:(RefSeq accession:NP_057316; substrate region highlighted if known)
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MGFWILAILT ILMYSTAAKF SKQSWGLENE ALIVRCPRQG KPSYTVDWYY SQTNKSIPTQ
ERNRVFASGQ LLKFLPAAVA DSGIYTCIVR SPTFNRTGYA NVTIYKKQSD CNVPDYLMYS
TVSGSEKNSK IYCPTIDLYN WTAPLEWFKN CQALQGSRYR AHKSFLVIDN VMTEDAGDYT
CKFIHNENGA NYSVTATRSF TVKDEQGFSL FPVIGAPAQN EIKEVEIGKN ANLTCSACFG
KGTQFLAAVL WQLNGTKITD FGEPRIQQEE GQNQSFSNGL ACLDMVLRIA DVKEEDLLLQ
YDCLALNLHG LRRHTVRLSR KNPIDHHSIY CIIAVCSVFL MLINVLVIIL KMFWIEATLL
WRDIAKPYKT RNDGKLYDAY VVYPRNYKSS TDGASRVEHF VHQILPDVLE NKCGYTLCIY
GRDMLPGEDV VTAVETNIRK SRRHIFILTP QITHNKEFAY EQEVALHCAL IQNDAKVILI
EMEALSELDM LQAEALQDSL QHLMKVQGTI KWREDHIANK RSLNSKFWKH VRYQMPVPSK
IPRKASSLTP LAAQKQ
Records:
Category Evidence Reference
A Peptide affinity isolation Yaoi T, Chamnongpol S, Jiang X, Li X., Src homology 2 domain-based high throughput assays for profiling downstream molecules in receptor tyrosine kinase pathways, [16477079]
End of Record Details