ul_3362----
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PPBD protein
Gene name GRB7( Description: growth factor receptor-bound protein 7. )
Synonyms B47; Epidermal growth factor receptor GRB-7; GRB7 adapter protein
GO annotations GO_component:
GO_function:SH3/SH2 adaptor activity [PMID 9710451]
GO_process: epidermal growth factor receptor signaling pathway [PMID 9710451]; intracellular signaling cascade; signal transduction
RefSeq accession NP_005301
SwissProt accession Q14451
Substrate protein
Gene name EPHB1( Description: EPH receptor B1. )
Synonyms EC 2.7.10.1; ELK; EPHT2; FLJ37986; HEK6; Hek6; NET; Tyrosine-protein kinase receptor EPH-2
GO annotations GO_component: integral to plasma membrane [PMID 8666391]; plasma membrane [PMID 8666391]
GO_function:ATP binding; ephrin receptor activity; nucleotide binding; protein binding [PMID 8798570]; receptor activity; transferase activity
GO_process: nervous system development [PMID 8666391]; protein amino acid phosphorylation; signal transduction [PMID 8666391]; transmembrane receptor protein tyrosine kinase signaling pathway
RefSeq accession NP_004432
SwissProt accession P54762
Sequence:(RefSeq accession:NP_004432; substrate region highlighted if known)
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MALDYLLLLL LASAVAAMEE TLMDTRTATA ELGWTANPAS GWEEVSGYDE NLNTIRTYQV
CNVFEPNQNN WLLTTFINRR GAHRIYTEMR FTVRDCSSLP NVPGSCKETF NLYYYETDSV
IATKKSAFWS EAPYLKVDTI AADESFSQVD FGGRLMKVNT EVRSFGPLTR NGFYLAFQDY
GACMSLLSVR VFFKKCPSIV QNFAVFPETM TGAESTSLVI ARGTCIPNAE EVDVPIKLYC
NGDGEWMVPI GRCTCKPGYE PENSVACKAC PAGTFKASQE AEGCSHCPSN SRSPAEASPI
CTCRTGYYRA DFDPPEVACT SVPSGPRNVI SIVNETSIIL EWHPPRETGG RDDVTYNIIC
KKCRADRRSC SRCDDNVEFV PRQLGLTECR VSISSLWAHT PYTFDIQAIN GVSSKSPFPP
QHVSVNITTN QAAPSTVPIM HQVSATMRSI TLSWPQPEQP NGIILDYEIR YYEKEHNEFN
SSMARSQTNT ARIDGLRPGM VYVVQVRART VAGYGKFSGK MCFQTLTDDD YKSELREQLP
LIAGSAAAGV VFVVSLVAIS IVCSRKRAYS KEAVYSDKLQ HYSTGRGSPG MKIYIDPFTY
EDPNEAVREF AKEIDVSFVK IEEVIGAGEF GEVYKGRLKL PGKREIYVAI KTLKAGYSEK
QRRDFLSEAS IMGQFDHPNI IRLEGVVTKS RPVMIITEFM ENGALDSFLR QNDGQFTVIQ
LVGMLRGIAA GMKYLAEMNY VHRDLAARNI LVNSNLVCKV SDFGLSRYLQ DDTSDPTYTS
SLGGKIPVRW TAPEAIAYRK FTSASDVWSY GIVMWEVMSF GERPYWDMSN QDVINAIEQD
YRLPPPMDCP AALHQLMLDC WQKDRNSRPR FAEIVNTLDK MIRNPASLKT VATITAVPSQ
PLLDRSIPDF TAFTTVDDWL SAIKMVQYRD SFLTAGFTSL QLVTQMTSED LLRIGITLAG
HQKKILNSIH SMRVQISQSP TAMA
Records:
Category Evidence Reference
A Mutagenesis Han DC, Shen TL, Miao H, Wang B, Guan JL., EphB1 associates with Grb7 and regulates cell migration, [12223469]
End of Record Details