ul_3441----
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PPBD protein
Gene name INPP5D( Description: inositol polyphosphate-5-phosphatase, 145kDa. )
Synonyms MGC104855; MGC142140; MGC142142; SHIP; SHIP1; SIP-145; hp51CN
GO annotations GO_component:
GO_function:inositol or phosphatidylinositol phosphatase activity; inositol-polyphosphate 5-phosphatase activity [PMID 8769125]
GO_process: intracellular signaling cascade; phosphate metabolism [PMID 8769125]
RefSeq accession NP_005532
SwissProt accession Q13544
Substrate protein
Gene name CD244( Description: CD244 molecule, natural killer cell receptor 2B4. )
Synonyms 2B4; CD244 antigen; NAIL; NK cell activation-inducing ligand; NK cell type I receptor protein 2B4; NKR2B4; Nmrk; SLAMF4; h2B4
GO annotations GO_component: integral to membrane; membrane
GO_function:protein binding [PMID 10358138]; receptor activity [PMID 10358138]
GO_process: cellular defense response; signal transduction [PMID 10358138]
RefSeq accession NP_057466
SwissProt accession Q9BZW8
GO Pathway:
GO:0007242     intracellular signaling cascade
Sequence:(RefSeq accession:NP_057466; substrate region highlighted if known)
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MLGQVVTLIL LLLLKVYQGK GCQGSADHVV SISGVPLQLQ PNSIQTKVDS IAWKKLLPSQ
NGFHHILKWE NGSLPSNTSN DRFSFIVKNL SLLIKAAQQQ DSGLYCLEVT SISGKVQTAT
FQVFVFDKVE KPRLQGQGKI LDRGRCQVAL SCLVSRDGNV SYAWYRGSKL IQTAGNLTYL
DEEVDINGTH TYTCNVSNPV SWESHTLNLT QDCQNAHQEF RFWPFLVIIV ILSALFLGTL
ACFCVWRRKR KEKQSETSPK EFLTIYEDVK DLKTRRNHEQ EQTFPGGGST IYSMIQSQSS
APTSQEPAYT LYSLIQPSRK SGSRKRNHSP SFNSTIYEVI GKSQPKAQNP ARLSRKELEN
FDVYS
Records:
Category Evidence Reference
A Peptide library Li C, Iosef C, Jia CY, Han VK, Li SS., Dual functional roles for the X-linked lymphoproliferative syndrome gene product SAP/SH2D1A in signaling through the signaling lymphocyte activation molecule (SLAM) family of immune receptors, [12458214]
End of Record Details