ul_3445----
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PPBD protein
Gene name INPP5D( Description: inositol polyphosphate-5-phosphatase, 145kDa. )
Synonyms MGC104855; MGC142140; MGC142142; SHIP; SHIP1; SIP-145; hp51CN
GO annotations GO_component:
GO_function:inositol or phosphatidylinositol phosphatase activity; inositol-polyphosphate 5-phosphatase activity [PMID 8769125]
GO_process: intracellular signaling cascade; phosphate metabolism [PMID 8769125]
RefSeq accession NP_005532
SwissProt accession Q13544
Substrate protein
Gene name LY9( Description: lymphocyte antigen 9. )
Synonyms CD229; CD229 antigen; Cell-surface molecule Ly-9; Lymphocyte antigen 9; SLAMF3; hly9; mLY9
GO annotations GO_component: integral to membrane; membrane
GO_function:protein binding
GO_process: cell adhesion; immunoglobulin mediated immune response
RefSeq accession NP_002339
SwissProt accession Q9HBG7
GO Pathway:
GO:0007242     intracellular signaling cascade
Sequence:(RefSeq accession:NP_002339; substrate region highlighted if known)
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MVAPKSHTDD WAPGPFSSKP QRSQLQIFSS VLQTSLLFLL MGLRASGKDS APTVVSGILG
GSVTLPLNIS VDTEIENVIW IGPKNALAFA RPKENVTIMV KSYLGRLDIT KWSYSLCISN
LTLNDAGSYK AQINQRNFEV TTEEEFTLFV YEQLQEPQVT MKSVKVSENF SCNITLMCSV
KGAEKSVLYS WTPREPHASE SNGGSILTVS RTPCDPDLPY ICTAQNPVSQ RSSLPVHVGQ
FCTDPGASRG GTTGETVVGV LGEPVTLPLA LPACRDTEKV VWLFNTSIIS KEREEAATAD
PLIKSRDPYK NRVWVSSQDC SLKISQLKIE DAGPYHAYVC SEASSVTSMT HVTLLIYRRL
RKPKITWSLR HSEDGICRIS LTCSVEDGGN TVMYTWTPLQ KEAVVSQGES HLNVSWRSSE
NHPNLTCTAS NPVSRSSHQF LSENICSGPE RNTKLWIGLF LMVCLLCVGI FSWCIWKRKG
RCSVPAFCSS QAEAPADTPE PTAGHTLYSV LSQGYEKLDT PLRPARQQPT PTSDSSSDSN
LTTEEDEDRP EVHKPISGRY EVFDQVTQEG AGHDPAPEGQ ADYDPVTPYV TEVESVVGEN
TMYAQVFNLQ GKTPVSQKEE SSATIYCSIR KPQVVPPPQQ NDLEIPESPT YENFT
Records:
Category Evidence Reference
A Peptide library Li C, Iosef C, Jia CY, Han VK, Li SS., Dual functional roles for the X-linked lymphoproliferative syndrome gene product SAP/SH2D1A in signaling through the signaling lymphocyte activation molecule (SLAM) family of immune receptors, [12458214]
End of Record Details