ul_3762----
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PPBD protein
Gene name LYN( Description: v-yes-1 Yamaguchi sarcoma viral related oncogene homolog. )
Synonyms FLJ26625; JTK8
GO annotations GO_component: cytoplasm; nucleus
GO_function:ATP binding; erythropoietin receptor binding; nucleotide binding; protein binding [PMID 7859737] [PMID 9020138]; receptor signaling protein tyrosine kinase activity [PMID 10748115]; transferase activity
GO_process: erythrocyte differentiation; hemoglobin biosynthesis; intracellular signaling cascade; positive regulation of cell proliferation; positive regulation of tyrosine phosphorylation of STAT protein; protein amino acid phosphorylation [PMID 3561390]; response to hormone stimulus
RefSeq accession NP_002341
SwissProt accession P07948
Substrate protein
Gene name PRKCD( Description: protein kinase C, delta. )
Synonyms EC 2.7.11.13; MAY1; MGC49908; nPKC-delta
GO annotations GO_component: cytoplasm [PMID 16611985]; membrane; nucleus [PMID 16611985]
GO_function:ATP binding; diacylglycerol binding; diacylglycerol-activated phospholipid-dependent protein kinase C activity [PMID 8357834]; enzyme activator activity [PMID 16611985]; enzyme binding [PMID 16611985]; metal ion binding; nucleotide binding; protein C-terminus binding [PMID 16611985]; protein serine/threonine kinase activity; transferase activity; zinc ion binding
GO_process: intracellular signaling cascade; protein amino acid phosphorylation [PMID 16611985]; protein stabilization [PMID 16611985]
RefSeq accession NP_006245
SwissProt accession Q05655
GO Pathway:
GO:0006468     protein amio acid phosphorylation
Sequence:(RefSeq accession:NP_006245; substrate region highlighted if known)
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MAPFLRIAFN SYELGSLQAE DEANQPFCAV KMKEALSTER GKTLVQKKPT MYPEWKSTFD
AHIYEGRVIQ IVLMRAAEEP VSEVTVGVSV LAERCKKNNG KAEFWLDLQP QAKVLMSVQY
FLEDVDCKQS MRSEDEAKFP TMNRRGAIKQ AKIHYIKNHE FIATFFGQPT FCSVCKDFVW
GLNKQGYKCR QCNAAIHKKC IDKIIGRCTG TAANSRDTIF QKERFNIDMP HRFKVHNYMS
PTFCDHCGSL LWGLVKQGLK CEDCGMNVHH KCREKVANLC GINQKLLAEA LNQVTQRASR
RSDSASSEPV GIYQGFEKKT GVAGEDMQDN SGTYGKIWEG SSKCNINNFI FHKVLGKGSF
GKVLLGELKG RGEYFAIKAL KKDVVLIDDD VECTMVEKRV LTLAAENPFL THLICTFQTK
DHLFFVMEFL NGGDLMYHIQ DKGRFELYRA TFYAAEIMCG LQFLHSKGII YRDLKLDNVL
LDRDGHIKIA DFGMCKENIF GESRASTFCG TPDYIAPEIL QGLKYTFSVD WWSFGVLLYE
MLIGQSPFHG DDEDELFESI RVDTPHYPRW ITKESKDILE KLFEREPTKR LGVTGNIKIH
PFFKTINWTL LEKRRLEPPF RPKVKSPRDY SNFDQEFLNE KARLSYSDKN LIDSMDQSAF
AGFSFVNPKF EHLLED
Records:
Category Evidence Reference
A Mutagenesis Song JS, Swann PG, Szallasi Z, Blank U, Blumberg PM, Rivera J., Tyrosine phosphorylation-dependent and -independent associations of protein kinase C-delta with Src family kinases in the RBL-2H3 mast cell line: regulation of Src family kinase activity by protein kinase C-delta, [9692543]
End of Record Details