ul_3828----
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PPBD protein
Gene name NCK1( Description: NCK adaptor protein 1. )
Synonyms MGC12668; NCK; NCK adaptor protein 1; NCKalpha; SH2/SH3 adaptor protein NCK-alpha
GO annotations GO_component: cytoplasm [PMID 12110186]
GO_function:cytoskeletal adaptor activity [PMID 12110186]; receptor binding [PMID 12110186]; receptor signaling complex scaffold activity [PMID 12110186]
GO_process: intracellular signaling cascade; positive regulation of actin filament polymerization [PMID 12110186]; positive regulation of T cell proliferation [PMID 12110186]; signal complex formation [PMID 12110186]; T cell activation [PMID 12110186]
RefSeq accession NP_006144
SwissProt accession P16333
Substrate protein
Gene name MMTVgp3( Description: Pr77. )
Synonyms
GO annotations GO_component:
GO_function:
GO_process:
RefSeq accession NP_056882
SwissProt accession
Sequence:(RefSeq accession:NP_056882; substrate region highlighted if known)
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MGVSGSKGQK LFVSVLQRLL SERGLHVKES SAIEFYQFLI KVSPWFPEEG GLNLQDWKRV
GREMKRYAAE HGTDSIPKQA YPIWLQLREI LTEQSDLVLL SAEAKSVTEE ELEEGLTGLL
STSSQEKTYG TRGTAYAEID TEVDKLSEHI YDEPYEEKEK ADKNEEKDHV RKIKKVVQRK
ENSEGKRKEK DSKAFLATDW NDDDLSPEDW DDLEEQAAHY HDDDELILPV KRKVVKKKPQ
ALRRKPLPPV GFAGAMAEAR EKGDLTFTFP VVFMGESDED DTPVWEPLPL KTLKELQSAV
RTMGPSAPYT LQVVDMVASQ WLTPSDWHQT ARATLSPGDY VLWRTEYEEK SKEMVQKAAG
KRKGKVSLDM LLGTGQFLSP SSQIKLSKDV LKDVTTNAVL AWRAIPPPGV KKTVLAGLKQ
GNEESYETFI SRLEEAVYRM MPRGEGSDIL IKQLAWENAN SLCQDLIRPI RKTGTIQDYI
RACLDASPAV VQGMAYAAAM RGQKYSTFVK QTYGGGKGGQ GAEGPVCFSC GKTGHIRKDC
KDEKGSKRAP PGLCPRCKKG YHWKSECKSK FDKDGNPLPP LETNAENSKN L
Records:
Category Evidence Reference
A Inference Songyang Z, Shoelson SE, Chaudhuri M, Gish G, Pawson T, Haser WG, King F, Roberts T, Ratnofsky S, Lechleider RJ, et al., SH2 domains recognize specific phosphopeptide sequences, [7680959]
End of Record Details