ul_4148----
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PPBD protein
Gene name PIK3R1( Description: coilin. )
Synonyms CLN80; PI3-kinase p85 subunit alpha; PI3K; PtdIns-3-kinase p85-alpha; p80-coilin; p85a
GO annotations GO_component: intracellular; phosphoinositide 3-kinase complex; phosphoinositide 3-kinase complex, class IA
GO_function:ErbB-3 class receptor binding [PMID 10572067]; insulin binding [PMID 8440175]; insulin receptor binding [PMID 7537849] [PMID 8276809]; insulin receptor substrate binding; insulin-like growth factor receptor binding [PMID 7541045]; kinase activity; phosphatidylinositol binding; phosphoinositide 3-kinase regulator activity; protein phosphatase binding [PMID 14699157]
GO_process: insulin receptor signaling pathway [PMID 8276809]; insulin-like growth factor receptor signaling pathway [PMID 7541045]; intracellular signaling cascade; phosphoinositide phosphorylation
RefSeq accession NP_852556
SwissProt accession P27986
Substrate protein
Gene name Cd19( Description: CD19 antigen. )
Synonyms AW495831
GO annotations GO_component: external side of plasma membrane; integral to membrane; membrane
GO_function:
GO_process:
RefSeq accession NP_033974
SwissProt accession
Sequence:(RefSeq accession:NP_033974; substrate region highlighted if known)
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MPSPLPVSFL LFLTLVGGRP QKSLLVEVEE GGNVVLPCLP DSSPVSSEKL AWYRGNQSTP
FLELSPGSPG LGLHVGSLGI LLVIVNVSDH MGGFYLCQKR PPFKDIWQPA WTVNVEDSGE
MFRWNASDVR DLDCDLRNRS SGSHRSTSGS QLYVWAKDHP KVWGTKPVCA PRGSSLNQSL
INQDLTVAPG STLWLSCGVP PVPVAKGSIS WTHVHPRRPN VSLLSLSLGG EHPVREMWVW
GSLLLLPQAT ALDEGTYYCL RGNLTIERHV KVIARSAVWL WLLRTGGWIV PVVTLVYVIF
CMVSLVAFLY CQRAFILRRK RKRMTDPARR FFKVTPPSGN GTQNQYGNVL SLPTSTSGQA
HAQRWAAGLG SVPGSYGNPR IQVQDTGAQS HETGLEEEGE AYEEPDSEEG SEFYENDSNL
GQDQVSQDGS GYENPEDEPM GPEEEDSFSN AESYENADEE LAQPVGRMMD FLSPHGSAWD
PSREASSLGS QSYEDMRGIL YAAPQLHSIQ SGPSHEEDAD SYENMDKSDD LEPAWEGEGH
MGTWGTT
Records:
Category Evidence Reference
A Inference Songyang Z, Shoelson SE, Chaudhuri M, Gish G, Pawson T, Haser WG, King F, Roberts T, Ratnofsky S, Lechleider RJ, et al., SH2 domains recognize specific phosphopeptide sequences, [7680959]
End of Record Details